{"title":"Hypertension, diabetes, and cardiovascular disease nexus: investigating the role of urbanization and lifestyle in Cabo Verde.","authors":"Aaron Kobina Christian, Akosua Afriyie Osei-Appaw, Ruth Tobi Sawyerr, Martin Wiredu Agyekum","doi":"10.1080/16549716.2024.2414524","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Although hypertension and diabetes are known to increase cardiovascular disease risk, the influencing and underlying factors remain unclear.</p><p><strong>Objective: </strong>To examine the mediating effect of location of residence and the moderating effects of recommended lifestyle practices in the hypertension/diabetes and cardiovascular disease nexus.</p><p><strong>Material and methods: </strong>Data were drawn from 4,563 participants in Steps 1 and 2 of the 2020 World Health Organization's STEPS survey in Cabo Verde, with a subsample of 2,436 individuals completing Step 3. A logit regression model was employed to examine the correlations of cardiovascular disease, while structural equation modeling and interaction analysis were used to identify mediators and moderators within the explored relationships.</p><p><strong>Results: </strong>Living with hypertension and diabetes were both observed to increase the likelihood of having a cardiovascular disease [Coeff. (RSE), 0.46, (0.12), <i>p</i> < 0.001; 1.26, (0.14), <i>p</i> < 0.001, respectively]. We identify urbanicity as a potential mediator through which hypertension/diabetes leads to a cardiovascular disease and waist circumference as a moderator of hypertension/diabetes-cardiovascular nexus.</p><p><strong>Conclusion: </strong>These findings add to the toolset of public health practitioners and policymakers in formulating policies and interventions aimed at managing cardiovascular diseases, particularly in developing nations.</p>","PeriodicalId":49197,"journal":{"name":"Global Health Action","volume":"17 1","pages":"2414524"},"PeriodicalIF":2.6000,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639676/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global Health Action","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/16549716.2024.2414524","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/22 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Although hypertension and diabetes are known to increase cardiovascular disease risk, the influencing and underlying factors remain unclear.
Objective: To examine the mediating effect of location of residence and the moderating effects of recommended lifestyle practices in the hypertension/diabetes and cardiovascular disease nexus.
Material and methods: Data were drawn from 4,563 participants in Steps 1 and 2 of the 2020 World Health Organization's STEPS survey in Cabo Verde, with a subsample of 2,436 individuals completing Step 3. A logit regression model was employed to examine the correlations of cardiovascular disease, while structural equation modeling and interaction analysis were used to identify mediators and moderators within the explored relationships.
Results: Living with hypertension and diabetes were both observed to increase the likelihood of having a cardiovascular disease [Coeff. (RSE), 0.46, (0.12), p < 0.001; 1.26, (0.14), p < 0.001, respectively]. We identify urbanicity as a potential mediator through which hypertension/diabetes leads to a cardiovascular disease and waist circumference as a moderator of hypertension/diabetes-cardiovascular nexus.
Conclusion: These findings add to the toolset of public health practitioners and policymakers in formulating policies and interventions aimed at managing cardiovascular diseases, particularly in developing nations.
背景：尽管高血压和糖尿病会增加心血管疾病风险，但其影响因素和潜在因素仍不明确：尽管众所周知高血压和糖尿病会增加心血管疾病风险，但其影响因素和潜在因素仍不明确：研究高血压/糖尿病与心血管疾病关系中居住地的中介效应和推荐生活方式的调节效应：数据来自佛得角参加2020年世界卫生组织STEPS调查步骤1和步骤2的4563名参与者，以及完成步骤3的子样本2436人。采用对数回归模型来研究心血管疾病的相关性，同时采用结构方程模型和交互分析来确定所探讨关系中的中介和调节因素：结果：观察发现，患有高血压和糖尿病都会增加罹患心血管疾病的可能性[Coeff. (RSE)，0.46，(0.12)，p p 结论：这些研究结果为心血管疾病的研究提供了新的工具：这些发现为公共卫生从业人员和政策制定者制定旨在管理心血管疾病的政策和干预措施提供了工具，尤其是在发展中国家。
期刊介绍：
Global Health Action is an international peer-reviewed Open Access journal affiliated with the Unit of Epidemiology and Global Health, Department of Public Health and Clinical Medicine at Umeå University, Sweden. The Unit hosts the Umeå International School of Public Health and the Umeå Centre for Global Health Research.
Vision: Our vision is to be a leading journal in the global health field, narrowing health information gaps and contributing to the implementation of policies and actions that lead to improved global health.
Aim: The widening gap between the winners and losers of globalisation presents major public health challenges. To meet these challenges, it is crucial to generate new knowledge and evidence in the field and in settings where the evidence is lacking, as well as to bridge the gaps between existing knowledge and implementation of relevant findings. Thus, the aim of Global Health Action is to contribute to fuelling a more concrete, hands-on approach to addressing global health challenges. Manuscripts suggesting strategies for practical interventions and research implementations where none already exist are specifically welcomed. Further, the journal encourages articles from low- and middle-income countries, while also welcoming articles originated from South-South and South-North collaborations. All articles are expected to address a global agenda and include a strong implementation or policy component.
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