Complications of synchronous microwave ablation and biopsy versus microwave ablation alone for pulmonary sub-solid nodules: a retrospective, large sample, case-control study.

IF 2.9 2区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-11 DOI:10.21037/qims-24-906
Pikun Cao, Zhigang Wei, Guoliang Xue, Nan Wang, Zhichao Li, Yanting Hu, Gang Wang, Xin Ye
{"title":"Complications of synchronous microwave ablation and biopsy versus microwave ablation alone for pulmonary sub-solid nodules: a retrospective, large sample, case-control study.","authors":"Pikun Cao, Zhigang Wei, Guoliang Xue, Nan Wang, Zhichao Li, Yanting Hu, Gang Wang, Xin Ye","doi":"10.21037/qims-24-906","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This was a retrospective, large-sample, case-control study assessing the complications associated with synchronous microwave ablation (MWA) and biopsy for pulmonary sub-solid nodules or ground-glass nodules (GGNs) versus MWA alone. We aimed to verify the safety of synchronous MWA and biopsy for treating GGNs.</p><p><strong>Methods: </strong>From May 2020 to December 2021, 326 patients with GGNs were enrolled. Among them, 164 patients underwent MWA alone (group A) and 162 patients underwent synchronous MWA and biopsy (group B). We assessed the complications, technical success, and positivity rate of the biopsy.</p><p><strong>Results: </strong>The major complications were similar between the two groups, and included pneumothorax (group A <i>vs.</i> group B, 19.5% <i>vs.</i> 13.6%; P=0.150), hemothorax (0.6% <i>vs.</i> 1.2%; P=1.000), pleural effusion (1.2% <i>vs.</i> 0.6%; P=1.000), and pulmonary infection (4.9% <i>vs.</i> 6.2%; P=0.609). No massive hemoptysis, bronchopleural fistula, or air embolism developed. Minor complications including intrapulmonary hemorrhage (group A <i>vs.</i> group B, 28.7% <i>vs.</i> 62.3%, P<0.001), mild pneumothorax (20.7% <i>vs.</i> 29.6%, P=0.587), mild ipsilateral pleural effusion (30.5% <i>vs.</i> 27.8%, P=0.590), mild bilateral pleural effusion (16.5% <i>vs.</i> 22.2%, P=0.188), and subcutaneous emphysema (4.3% <i>vs.</i> 5.6%, P=0.498) were observed. The side effects, including pain, cough, post-ablation syndrome, and post-ablation chronic pain syndrome, were similar between the two groups. The positive diagnosis rate of biopsy in group B was 88.3%.</p><p><strong>Conclusions: </strong>Compared with MWA alone, synchronous MWA and biopsy did not increase the risk of major complications. Although some minor complications developed, synchronous MWA and biopsy is safe for treating pulmonary GGNs.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485351/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Quantitative Imaging in Medicine and Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/qims-24-906","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Background: This was a retrospective, large-sample, case-control study assessing the complications associated with synchronous microwave ablation (MWA) and biopsy for pulmonary sub-solid nodules or ground-glass nodules (GGNs) versus MWA alone. We aimed to verify the safety of synchronous MWA and biopsy for treating GGNs.

Methods: From May 2020 to December 2021, 326 patients with GGNs were enrolled. Among them, 164 patients underwent MWA alone (group A) and 162 patients underwent synchronous MWA and biopsy (group B). We assessed the complications, technical success, and positivity rate of the biopsy.

Results: The major complications were similar between the two groups, and included pneumothorax (group A vs. group B, 19.5% vs. 13.6%; P=0.150), hemothorax (0.6% vs. 1.2%; P=1.000), pleural effusion (1.2% vs. 0.6%; P=1.000), and pulmonary infection (4.9% vs. 6.2%; P=0.609). No massive hemoptysis, bronchopleural fistula, or air embolism developed. Minor complications including intrapulmonary hemorrhage (group A vs. group B, 28.7% vs. 62.3%, P<0.001), mild pneumothorax (20.7% vs. 29.6%, P=0.587), mild ipsilateral pleural effusion (30.5% vs. 27.8%, P=0.590), mild bilateral pleural effusion (16.5% vs. 22.2%, P=0.188), and subcutaneous emphysema (4.3% vs. 5.6%, P=0.498) were observed. The side effects, including pain, cough, post-ablation syndrome, and post-ablation chronic pain syndrome, were similar between the two groups. The positive diagnosis rate of biopsy in group B was 88.3%.

Conclusions: Compared with MWA alone, synchronous MWA and biopsy did not increase the risk of major complications. Although some minor complications developed, synchronous MWA and biopsy is safe for treating pulmonary GGNs.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
肺实性结节下同步微波消融和活检与单纯微波消融的并发症:一项回顾性、大样本、病例对照研究。
背景:这是一项回顾性、大样本、病例对照研究,评估了同步微波消融(MWA)和活组织检查治疗肺实皮下结节或磨玻璃结节(GGNs)与单纯微波消融相比的并发症。我们旨在验证同步微波消融和活组织检查治疗GGNs的安全性:2020年5月至2021年12月,326名GGNs患者入组。其中,164 名患者单独接受了 MWA(A 组),162 名患者接受了同步 MWA 和活组织检查(B 组)。我们对并发症、技术成功率和活检阳性率进行了评估:两组患者的主要并发症相似,包括气胸(A 组对 B 组,19.5% 对 13.6%;P=0.150)、血胸(0.6% 对 1.2%;P=1.000)、胸腔积液(1.2% 对 0.6%;P=1.000)和肺部感染(4.9% 对 6.2%;P=0.609)。没有出现大咯血、支气管胸膜瘘或空气栓塞。观察到的轻微并发症包括肺内出血(A 组对 B 组,28.7% 对 62.3%,Pvs. 29.6%,P=0.587)、轻度同侧胸腔积液(30.5% 对 27.8%,P=0.590)、轻度双侧胸腔积液(16.5% 对 22.2%,P=0.188)和皮下气肿(4.3% 对 5.6%,P=0.498)。两组患者的副作用相似,包括疼痛、咳嗽、消融术后综合征和消融术后慢性疼痛综合征。B组活检阳性诊断率为88.3%:结论:与单纯 MWA 相比,同步 MWA 和活组织检查不会增加主要并发症的风险。结论:与单纯 MWA 相比,同步 MWA 和活组织检查不会增加主要并发症的风险,虽然会出现一些轻微并发症,但同步 MWA 和活组织检查对治疗肺 GGNs 是安全的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Quantitative Imaging in Medicine and Surgery
Quantitative Imaging in Medicine and Surgery Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
4.20
自引率
17.90%
发文量
252
期刊介绍: Information not localized
期刊最新文献
Comparison of single shot and multishot diffusion-weighted imaging in 5-T magnetic resonance imaging for brain disease diagnosis. Complications of synchronous microwave ablation and biopsy versus microwave ablation alone for pulmonary sub-solid nodules: a retrospective, large sample, case-control study. Congenital uterine arteriovenous malformation treated by hysterectomy: a description of two cases. Diagnostic value of a magnetic resonance imaging (MRI)-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis. Dilated multi-scale residual attention (DMRA) U-Net: three-dimensional (3D) dilated multi-scale residual attention U-Net for brain tumor segmentation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1