Diagnostic value of a magnetic resonance imaging (MRI)-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis.

IF 2.9 2区 医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Quantitative Imaging in Medicine and Surgery Pub Date : 2024-10-01 Epub Date: 2024-09-26 DOI:10.21037/qims-24-532
Dandan Yang, Chuan Liu, Qiaojun Hu
{"title":"Diagnostic value of a magnetic resonance imaging (MRI)-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis.","authors":"Dandan Yang, Chuan Liu, Qiaojun Hu","doi":"10.21037/qims-24-532","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Many studies have explored the application of the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score as a tool for opportunistic osteoporosis screening before spine surgery. We aimed to conduct a systematic review and meta-analysis of studies to determine the diagnostic value of the VBQ score for bone mineral density (BMD) assessment.</p><p><strong>Methods: </strong>The PubMed, EBSCO, Ovid, Web of Science, Cochrane Library, Wanfang, China National Knowledge Infrastructure, Chinese Science and Technology Periodical databases were searched to retrieve original studies on VBQ and BMD published from inception to 31 December 2023 with no restrictions on language and the reference standard of BMD. The quality of the included articles was assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2). Summary accuracy metrics were obtained by bivariate random-effects meta-analysis. The area under the curve (AUC) of the summary receiver operating characteristic (SROC) analysis was used to evaluate the performance of the VBQ score. Meta-regression and subgroup analyses were performed to examine the source of heterogeneity.</p><p><strong>Results: </strong>In total, 23 studies, comprising 2981 patients, from 2022 to 2023, of high- or medium-to-high scientific quality were included in the meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratio (DOR) of the VBQ score in the assessment of BMD were 0.77 [95% confidence interval (CI), 0.73-0.81; P<0.001], 0.65 (95% CI, 0.59-0.71; P<0.001), and 6.49 (95% CI, 4.82-8.73; P<0.001), respectively, with an area under the SROC curve of 0.78 (95% CI, 0.74-0.82; P<0.001). The presence of heterogeneity was found to have a significant association with factors such as the reference standard, sex, mean age, region of publication, VBQ method, and magnet field strength.</p><p><strong>Conclusions: </strong>The MRI-based VBQ score has some diagnostic value in detecting osteoporosis. The VBQ score could be used as a tool for opportunistic osteoporosis screening before spine surgery.</p>","PeriodicalId":54267,"journal":{"name":"Quantitative Imaging in Medicine and Surgery","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485385/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Quantitative Imaging in Medicine and Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/qims-24-532","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/26 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Many studies have explored the application of the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score as a tool for opportunistic osteoporosis screening before spine surgery. We aimed to conduct a systematic review and meta-analysis of studies to determine the diagnostic value of the VBQ score for bone mineral density (BMD) assessment.

Methods: The PubMed, EBSCO, Ovid, Web of Science, Cochrane Library, Wanfang, China National Knowledge Infrastructure, Chinese Science and Technology Periodical databases were searched to retrieve original studies on VBQ and BMD published from inception to 31 December 2023 with no restrictions on language and the reference standard of BMD. The quality of the included articles was assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2). Summary accuracy metrics were obtained by bivariate random-effects meta-analysis. The area under the curve (AUC) of the summary receiver operating characteristic (SROC) analysis was used to evaluate the performance of the VBQ score. Meta-regression and subgroup analyses were performed to examine the source of heterogeneity.

Results: In total, 23 studies, comprising 2981 patients, from 2022 to 2023, of high- or medium-to-high scientific quality were included in the meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratio (DOR) of the VBQ score in the assessment of BMD were 0.77 [95% confidence interval (CI), 0.73-0.81; P<0.001], 0.65 (95% CI, 0.59-0.71; P<0.001), and 6.49 (95% CI, 4.82-8.73; P<0.001), respectively, with an area under the SROC curve of 0.78 (95% CI, 0.74-0.82; P<0.001). The presence of heterogeneity was found to have a significant association with factors such as the reference standard, sex, mean age, region of publication, VBQ method, and magnet field strength.

Conclusions: The MRI-based VBQ score has some diagnostic value in detecting osteoporosis. The VBQ score could be used as a tool for opportunistic osteoporosis screening before spine surgery.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
基于磁共振成像(MRI)的脊椎骨质量评分对骨矿物质密度评估的诊断价值:最新系统综述和荟萃分析。
背景:许多研究探讨了基于磁共振成像(MRI)的椎体骨质量(VBQ)评分作为脊柱手术前骨质疏松症机会性筛查工具的应用。我们旨在对相关研究进行系统回顾和荟萃分析,以确定 VBQ 评分在骨矿物质密度(BMD)评估中的诊断价值:方法:检索PubMed、EBSCO、Ovid、Web of Science、Cochrane Library、万方、中国国家知识基础设施、中国科技期刊等数据库,检索自开始至2023年12月31日发表的关于VBQ和BMD的原始研究,语言和BMD参考标准不限。纳入文章的质量采用诊断准确性研究质量评估(QUADAS-2)进行评估。通过双变量随机效应荟萃分析得出了准确性指标。汇总接收者操作特征(SROC)分析的曲线下面积(AUC)用于评估VBQ评分的性能。为了研究异质性的来源,还进行了元回归和亚组分析:荟萃分析共纳入了 23 项研究,包括 2981 名患者,研究时间为 2022 年至 2023 年,研究质量为高或中高。VBQ评分在评估BMD方面的汇总灵敏度、特异性和诊断几率比(DOR)均为0.77[95%置信区间(CI),0.73-0.81;PC结论:基于磁共振成像的 VBQ 评分在检测骨质疏松症方面具有一定的诊断价值。VBQ 评分可作为脊柱手术前骨质疏松症机会性筛查的工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Quantitative Imaging in Medicine and Surgery
Quantitative Imaging in Medicine and Surgery Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
4.20
自引率
17.90%
发文量
252
期刊介绍: Information not localized
期刊最新文献
Comparison of single shot and multishot diffusion-weighted imaging in 5-T magnetic resonance imaging for brain disease diagnosis. Complications of synchronous microwave ablation and biopsy versus microwave ablation alone for pulmonary sub-solid nodules: a retrospective, large sample, case-control study. Congenital uterine arteriovenous malformation treated by hysterectomy: a description of two cases. Diagnostic value of a magnetic resonance imaging (MRI)-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis. Dilated multi-scale residual attention (DMRA) U-Net: three-dimensional (3D) dilated multi-scale residual attention U-Net for brain tumor segmentation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1