Neonatal Jaundice: A Study of the Incidence in Children of Rh (D) Negative and 0 Rh (D) Positive Mothers.

Josef Urbanec, Kateřina Chládková, Magdalena Chvílová Weberová, Sylva Skálová, Jan Kremláček
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Abstract

Despite advances in neonatal care, neonatal jaundice remains a common problem in maternity wards. The present retrospective epidemiological study collected data on a sample of 710 newborns and compared the incidence of neonatal jaundice in infants born to Rh (D) negative and 0 Rh (D) positive mothers. The primary aim was to determine whether the higher incidence of maternal alloimmunisation in newborns was causally related to a potentially higher incidence of neonatal jaundice in newborns of 0 Rh (D) positive mothers. To the end, we investigated a possible association between the incidence of neonatal jaundice in 0 Rh (D) positive mothers and the neonatal blood group. The incidence of neonatal jaundice was not found to differ between maternal blood groups. We discuss new preventive measures that may reduce the incidence of neonatal jaundice and thereby reduce the length of hospital stay.

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新生儿黄疸:关于 Rh (D) 阴性和 0 Rh (D) 阳性母亲所生子女发病率的研究。
尽管新生儿护理技术不断进步,但新生儿黄疸仍是产科病房的常见问题。这项回顾性流行病学研究收集了 710 名新生儿的样本数据,并比较了 Rh (D) 阴性母亲和 Rh (D) 阳性母亲所生婴儿的新生儿黄疸发病率。这项研究的主要目的是确定,新生儿中母体同种免疫发生率较高是否与 Rh (D) 阳性和 Rh (D) 阴性母亲的新生儿黄疸发生率较高有潜在的因果关系。为此,我们研究了 0 Rh (D) 阳性母亲的新生儿黄疸发生率与新生儿血型之间可能存在的关联。结果发现,不同血型母亲的新生儿黄疸发生率并无差异。我们讨论了可降低新生儿黄疸发病率从而缩短住院时间的新预防措施。
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