Addressing gaps in the diagnosis of TB in children.

J Hoffmann, C R Horsburgh
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Abstract

Since 2000, efforts to develop new treatments for TB have been promising, but diagnosing TB, especially in children, remains a challenge. This issue of the Journal includes the first in a series of articles related to TB in children, highlighting new diagnostic tests that do not rely on sputum, and have great potential for improving diagnosis and treatment initiation. Key to a reduction in TB prevalence, experts are engaging with communities to find undiagnosed cases and combat the stigma of TB. International collaborations are also central to integrating novel diagnostics and providing support for these vulnerable populations.

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缩小儿童结核病诊断方面的差距。
自 2000 年以来,开发结核病新疗法的工作取得了可喜的成果,但诊断结核病,尤其是儿童结核病仍是一项挑战。本期期刊收录了与儿童结核病相关的系列文章中的第一篇,重点介绍了不依赖痰液的新型诊断检测方法,这些方法在改善诊断和开始治疗方面具有巨大潜力。降低结核病发病率的关键在于专家与社区合作发现未确诊病例并消除结核病的耻辱感。国际合作对于整合新型诊断方法和为这些弱势群体提供支持也至关重要。
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Assessing the accuracy of the updated Fujifilm SILVAMP TB LAM II assay between lot numbers. Closing the gaps in childhood TB detection. Comparative efficacy of tetracyclines against isolates of Mycobacterium avium complex. Efficacy and safety data on pretomanid for drug-resistant TB. Ending the TB epidemic - what can we learn from the HIV epidemic?
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