Elizabethkingia meningoseptica in Dubai, United Arab Emirates: A 7-year multicenter study

IF 2.4 3区医学 Q2 INFECTIOUS DISEASES American journal of infection control Pub Date : 2024-10-23 DOI:10.1016/j.ajic.2024.10.016

Hawra Ali Hussain Alsayed MPharm , Narjes Saheb Sharif-Askari PhD , Fatemeh Saheb Sharif-Askari PhD , Rabih Halwani PhD

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Abstract

Background

Elizabethkingia meningoseptica (E. meningoseptica) is a gram-negative bacillus. Widely distributed in nature, it poses a significant threat as a nosocomial pathogen, particularly affecting immunocompromised neonates and the elderly.

Methods

This study aimed to describe the antimicrobial susceptibility and outcomes of E. meningoseptica infections over seven years in United Arab Emirates. A retrospective chart review study was conducted at four hospitals that are part of Dubai Academic Health Corporation.

Results

A total of 23 cases were observed during the study, 21 (91%) of which exhibited multidrug resistance. More than half of the cases required intensive care and mechanical ventilation (n = 13, 57%). The in-hospital mortality rate was 38% (n = 5) in adults and 20% (n = 2) in pediatrics.

Conclusions

E. meningoseptica is a significant nosocomial pathogen with high antibiotic resistance, posing severe risks to immunocompromised pediatric and adult patients. Effective management of E. meningoseptica requires vigilant monitoring, comprehensive control, and targeted therapies.

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阿拉伯联合酋长国迪拜的 Elizabethkingia Meningoseptica：一项为期 7 年的多中心研究。

脑膜炎伊丽莎白金杆菌是一种革兰氏阴性杆菌。它广泛分布于自然界，作为一种院内病原体，对免疫力低下的新生儿和老年人的影响尤为严重。本研究旨在描述阿联酋七年来脑膜炎双球菌感染的抗菌药敏感性和结果。研究期间共观察到 23 例病例，其中 21 例（91%）表现出多药耐药性。一半以上的病例需要重症监护和机械通气（13 例，57%）。观察到的院内死亡率为：成人 38%（5 人），儿童 20%（2 人）。脑膜脑炎感染的有效治疗需要警惕性监测、全面控制和针对性治疗。

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来源期刊

American journal of infection control 医学-传染病学

CiteScore

7.40

自引率

4.10%

发文量

479

审稿时长

24 days

期刊介绍： AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)