Dynapenic abdominal obesity and activities of daily living disability among older adults residing in low- and middle-income countries

IF 3.4 3区 医学 Q2 GERIATRICS & GERONTOLOGY Aging Clinical and Experimental Research Pub Date : 2024-10-26 DOI:10.1007/s40520-024-02864-x
Lee Smith, Guillermo F. López Sánchez, Pinar Soysal, Karel Kostev, Louis Jacob, Nicola Veronese, Mark A. Tully, Laurie Butler, Yvonne Barnett, Damiano Pizzol, Jae Il Shin, Ai Koyanagi
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Abstract

Background

Dynapenic abdominal obesity (DAO) may be associated with an increased risk of disability. However, to date, this has not been investigated in low- and middle-income countries (LMICs), while the mediators are largely unknown.

Aims

Therefore, we aimed to investigate the association between DAO and activities of daily living (ADL) disability, and to identify potential mediators among older adults from six LMICs.

Methods

Cross-sectional, nationally representative data from the WHO Study on global AGEing and adult health were analyzed. Data on 20,198 adults aged ≥ 60 years were analyzed [mean (SD) age 69.3 (13.1) years; 54.1% females]. Dynapenia was defined as handgrip strength of < 26 kg for men and < 16 kg for women. Abdominal obesity was defined as waist circumference of > 88 cm for women and > 102 cm for men. DAO was defined as having both dynapenia and abdominal obesity. Disability was defined as severe or extreme difficulty in conducting at least one of six types of ADL. Multivariable logistic regression and mediation analysis were conducted.

Results

Compared to no dynapenia and no abdominal obesity, DAO was significantly associated with 2.08 (95%CI = 1.37–3.17) times higher odds for ADL disability Mediation analysis showed that diabetes (mediated percentage 4.7%), hypertension (7.2%), and angina (7.7%) were significant mediators in the association between DAO and ADL disability.

Conclusions

DAO was associated with increased odds for ADL disability among older adults from LMICs. Future longitudinal studies are warranted to assess temporal associations, and whether addressing or preventing DAO can impact on future occurrence of disability.

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居住在中低收入国家的老年人腹部动态肥胖与日常生活活动障碍。
背景:腹部动态肥胖(DAO)可能与残疾风险增加有关。目的:因此,我们旨在调查腹部动态肥胖与日常生活活动(ADL)残疾之间的关系,并确定六个低收入和中等收入国家老年人中的潜在中介因素:对世界卫生组织全球老龄化与成人健康研究中具有全国代表性的横断面数据进行了分析。分析了 20,198 名年龄≥ 60 岁的成年人的数据[平均(标清)年龄为 69.3 (13.1) 岁;54.1% 为女性]。女性握力88厘米,男性握力大于102厘米,即为 "握力不足"。DAO定义为同时患有动力不足症和腹部肥胖症。残疾的定义是在六种日常活动能力中至少有一种出现严重或极度困难。研究人员进行了多变量逻辑回归和中介分析:结果:与无动态腹部肥胖症和无腹部肥胖症相比,DAO 与 ADL 残疾几率增加 2.08 倍(95%CI = 1.37-3.17 倍)显著相关:DAO与低收入和中等收入国家老年人ADL残疾几率增加有关。今后有必要开展纵向研究,以评估时间上的关联,以及解决或预防DAO是否会对未来残疾的发生产生影响。
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来源期刊
CiteScore
7.90
自引率
5.00%
发文量
283
审稿时长
1 months
期刊介绍: Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.
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