Association between Ward's triangle bone mineral density levels and abdominal aortic calcification: Data from the national health and nutrition examination survey 2013–2014

IF 2.9 Q3 NUTRITION & DIETETICS Clinical nutrition ESPEN Pub Date : 2024-10-24 DOI:10.1016/j.clnesp.2024.10.154
Mengmeng Wang , Degang Mo , Chi Zhou , Mengqi Guo , Wenqiang Zhang , Rui Chen , Jiachao Xu , Ning Zhang , Haichu Yu
{"title":"Association between Ward's triangle bone mineral density levels and abdominal aortic calcification: Data from the national health and nutrition examination survey 2013–2014","authors":"Mengmeng Wang ,&nbsp;Degang Mo ,&nbsp;Chi Zhou ,&nbsp;Mengqi Guo ,&nbsp;Wenqiang Zhang ,&nbsp;Rui Chen ,&nbsp;Jiachao Xu ,&nbsp;Ning Zhang ,&nbsp;Haichu Yu","doi":"10.1016/j.clnesp.2024.10.154","DOIUrl":null,"url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Despite extensive research into the cardiovascular implications of abdominal aortic calcification (AAC), there is a scarcity of robust studies exploring its association with Ward's triangle bone mineral density (BMD). This study aimed to evaluate this relationship in a nationally representative sample and compare the predictive value with femoral neck BMD and total femur BMD.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional analysis of 2013–2014 National Health and Nutrition Examination Survey (NHANES) data, utilizing a complex, stratified, multistage, cluster sampling design. BMD measurements at Ward's triangle, femoral neck, and total femur were assessed using DXA scans. AAC severity was defined by a Kauppila score of ≥5. Predictors of AAC-24 scores were identified through correlation and linear regression models. Stratified regression and restricted cubic splines were applied to explore subgroup and dose–response relationships.</div></div><div><h3>Results</h3><div>Of the 2965 participants representing 116, 562, 500 individuals in the U.S., 11 % had severe AAC. Ward's triangle BMD showed a significant negative association with AAC-24 scores (β = −1.90, 95 % CI: −2.80 to −1.00, P &lt; 0.002) and a reduced risk of severe AAC (OR = 0.85, 95 % CI: 0.76 to 0.95, P = 0.010). Non-linear associations were observed between Ward's triangle BMD and AAC outcomes. Ward's triangle BMD outperformed femoral neck and total femur BMD in predicting AAC.</div></div><div><h3>Conclusions</h3><div>Higher Ward's triangle BMD is linked to lower odds of severe AAC, highlighting its potential for improved early detection of AAC over femoral neck and total femur BMD. Healthcare providers should consider the implications of reduced Ward's triangle BMD for systemic atherosclerosis and recommend early AAC screening for enhanced cardiovascular risk management.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"64 ","pages":"Pages 344-357"},"PeriodicalIF":2.9000,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical nutrition ESPEN","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S240545772401492X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0

Abstract

Background & aims

Despite extensive research into the cardiovascular implications of abdominal aortic calcification (AAC), there is a scarcity of robust studies exploring its association with Ward's triangle bone mineral density (BMD). This study aimed to evaluate this relationship in a nationally representative sample and compare the predictive value with femoral neck BMD and total femur BMD.

Methods

We conducted a cross-sectional analysis of 2013–2014 National Health and Nutrition Examination Survey (NHANES) data, utilizing a complex, stratified, multistage, cluster sampling design. BMD measurements at Ward's triangle, femoral neck, and total femur were assessed using DXA scans. AAC severity was defined by a Kauppila score of ≥5. Predictors of AAC-24 scores were identified through correlation and linear regression models. Stratified regression and restricted cubic splines were applied to explore subgroup and dose–response relationships.

Results

Of the 2965 participants representing 116, 562, 500 individuals in the U.S., 11 % had severe AAC. Ward's triangle BMD showed a significant negative association with AAC-24 scores (β = −1.90, 95 % CI: −2.80 to −1.00, P < 0.002) and a reduced risk of severe AAC (OR = 0.85, 95 % CI: 0.76 to 0.95, P = 0.010). Non-linear associations were observed between Ward's triangle BMD and AAC outcomes. Ward's triangle BMD outperformed femoral neck and total femur BMD in predicting AAC.

Conclusions

Higher Ward's triangle BMD is linked to lower odds of severe AAC, highlighting its potential for improved early detection of AAC over femoral neck and total femur BMD. Healthcare providers should consider the implications of reduced Ward's triangle BMD for systemic atherosclerosis and recommend early AAC screening for enhanced cardiovascular risk management.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
沃德三角区骨矿密度水平与腹主动脉钙化之间的关系:来自 2013-2014 年全国健康与营养调查的数据。
背景与目的:尽管对腹主动脉钙化(AAC)对心血管的影响进行了广泛的研究,但很少有可靠的研究探讨其与沃德氏三角区骨矿物质密度(BMD)的关系。本研究旨在评估全国代表性样本中的这种关系,并比较其与股骨颈 BMD 和总股骨 BMD 的预测价值:我们对 2013-2014 年美国国家健康与营养调查 (NHANES) 数据进行了横断面分析,采用了复杂的分层、多阶段、群组抽样设计。使用 DXA 扫描评估了沃德三角区、股骨颈和全股骨的 BMD 测量值。AAC严重程度由Kauppila评分≥5来定义。通过相关性和线性回归模型确定了 AAC-24 评分的预测因素。应用分层回归和限制性立方样条来探讨亚组和剂量反应关系:在代表美国 1.165625 亿人的 2965 名参与者中,11% 的人患有严重的 AAC。Ward's 三角形 BMD 与 AAC-24 评分呈显著负相关(β = -1.90, 95% CI: -2.80 to -1.00, P < 0.002),并降低了严重 AAC 的风险(OR = 0.85, 95% CI: 0.76 to 0.95, P = 0.010)。Ward's 三角形 BMD 与 AAC 结果之间存在非线性关联。在预测 AAC 方面,Ward's 三角区 BMD 优于股骨颈和全股骨 BMD:结论:较高的沃德三角区 BMD 与较低的严重 AAC 发生几率有关,这表明沃德三角区 BMD 比股骨颈和股骨总 BMD 更有潜力提高 AAC 的早期发现率。医疗服务提供者应考虑沃德氏三角区 BMD 降低对全身动脉粥样硬化的影响,并建议进行早期 AAC 筛查,以加强心血管风险管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Clinical nutrition ESPEN
Clinical nutrition ESPEN NUTRITION & DIETETICS-
CiteScore
4.90
自引率
3.30%
发文量
512
期刊介绍: Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.
期刊最新文献
Pathophysiological Mechanisms of Gut Dysbiosis and Food Allergy and an Investigation of Probiotics as an Intervention for Atopic Disease. Gastrointestinal hormones and subjective ratings of appetite after low-carbohydrate vs low-fat low-energy diets in females with lipedema - a randomized controlled trial. Six-month trajectory of phase angle after cardiovascular surgery and associated factors of the recovery during cardiac rehabilitation: a retrospective cohort study. The SARC-F score may indirectly reflect the extracellular water-to-total body water ratio. The relationship between caloric intake and clinical outcomes in critically ill patients: A retrospective study.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1