Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial.

IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Clinical Oral Investigations Pub Date : 2024-10-27 DOI:10.1007/s00784-024-06006-5
Nawar Naguib Nawar, Mohamed Mohamed Elashiry, Ahmed El Banna, Shehabeldin Mohamed Saber, Edgar Schäfer
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Abstract

Objectives: This 2-part randomized parallel triple-blind clinical trial adopts a unique model assessing clinically-set hydraulic calcium silicate-based sealers (HCSBS) after different root canal dryness protocols and obturation techniques.

Methods: For the first phase of the study, 24 teeth scheduled for orthodontic extractions were allocated into four groups according to the canal dryness protocol and the obturation technique. G1 (CLC-AHP): cold lateral compaction (CLC) with AH Plus sealer, G2 (CLC-ES-SD): CLC with Endosequence (ES) after standard canal(s) dryness (SD); G3 (SC-ES-SD): matching single-cone (SC) with ES after SD; G4 (SC-ES-PD): as G3 but after partial canal(s) dryness (PD). Teeth were extracted after one month of clinical service and examined for intracanal voids by micro-CT (2D & 3D). For the 2nd phase, another 24 teeth were allocated into four groups according to the root canal dryness protocol and the HCSBS used (ES or CeraSeal (CeS)). Teeth were extracted after one month and sectioned vertically for energy dispersive X-ray (EDX)/scanning electron microscope (SEM) examination. One-way ANOVA with Games-Howell post-hoc test and Chi-square test with multiple z-tests were used for statistical analysis.

Results: SC-PD showed the highest percentage of voids (p < 0.05). MicroCT scans as well as EDX/SEM examination showed that PD resulted in significantly larger interfacial gaps (p < 0.001) with more hydration products at the sealer/dentin interface than SD.

Conclusions: Both tested dryness protocols allowed the hydration of HCSBS and the formation of hydration products, thus standard dryness is recommended to reduce the incidence of intracanal voids.

Clinical relevance: When using the single-cone obturation technique, intentional root canal moisture negatively affects the performance of HCSBS.

Protocol registration: http://www.

Clinicaltrials: gov, ID: NCT05808062.

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采用不同的管路干燥方案和封堵技术对临床固化液压封堵器进行体内外评估:随机临床试验。
目的:这项由两部分组成的随机平行三盲临床试验采用了一种独特的模式,评估不同根管干燥方案和封固技术后临床设置的液压硅酸钙基封固剂(HCSBS):在第一阶段研究中,根据根管干燥方案和封闭技术,将 24 颗计划进行正畸拔牙的牙齿分为四组。G1组(CLC-AHP):使用AH Plus封闭剂的冷侧压合(CLC);G2组(CLC-ES-SD):G3 (SC-ES-SD):在标准牙道干燥(SD)后使用 ES 进行匹配单锥体(SC);G4 (SC-ES-PD):与 G3 相同,但在部分牙道干燥(PD)后使用。临床服务一个月后拔除牙齿,并通过显微 CT(二维和三维)检查牙髓腔内的空隙。在第二阶段,根据根管干燥方案和使用的 HCSBS(ES 或 CeraSeal (CeS)),将另外 24 颗牙齿分为四组。一个月后拔出牙齿,垂直切片进行能量色散 X 射线(EDX)/扫描电子显微镜(SEM)检查。统计分析采用单因素方差分析和 Games-Howell 后验法,以及卡方检验和多重卡方检验:结果:SC-PD 显示出最高的空隙百分比(p 结论):两种测试的干燥方案都允许HCSBS水化并形成水化产物,因此建议使用标准干燥方案来降低龋洞内空洞的发生率:临床相关性:在使用单锥封堵技术时,故意使根管潮湿会对 HCSBS 的性能产生负面影响。协议注册:http://www.Clinicaltrials: gov,ID:NCT05808062。
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来源期刊
Clinical Oral Investigations
Clinical Oral Investigations 医学-牙科与口腔外科
CiteScore
6.30
自引率
5.90%
发文量
484
审稿时长
3 months
期刊介绍: The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.
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