Comparative study of 3D-T2WI vs. 3D-T2-FLAIR MRI in displaying human meningeal lymphatics vessels

IF 2.1 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical radiology Pub Date : 2025-02-01 DOI:10.1016/j.crad.2024.09.006

Y. Fang , Y. Sun , T. Lai , X. Song , T. Hu , Y. Zhao , Y. Lin , Q. Bao

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Abstract

Aim

Various magnetic resonance imaging (MRI) sequences can be utilized to visualize human meningeal lymphatic vessels (MLVs) for investigating the associations between MLVs and central nervous system (CNS) disorders. This study aimed to compare the quality of contrast-enhanced 3D-T2WI and 3D-T2-fluid-attenuated inversion recovery (FLAIR) MRI sequences to display human MLVs.

Materials and Methods

Sixty-two patients (27 males, 35 females; mean age 55.8 ± 14.9 years) underwent 3D-T2WI and 3D-T2-FLAIR scan in combination with Gd-DTPA injection to show MLVs.

Results

(1) The positivity rates of the 3D-T2WI sequence were 98.4%, 29.0%, and 46.8%, around the dural sinus, middle meningeal artery, and ethmoid sinus, respectively. The positivity rates of the 3D-T2-FLAIR sequence were 100%, 48.4%, and 66.1%, respectively. The positivity rate was significantly higher with the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence for the middle meningeal artery and ethmoid sinus regions (p < 0.05). (2) In patients with brain lesions and intracranial space-occupying lesions, the positivity rate was significantly higher with the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence for the middle meningeal artery and ethmoid sinus regions (p < 0.05). (3) The mean cross-sectional areas of MLVs around the dural sinus, middle meningeal artery, and ethmoid sinus were all higher using the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence at all three sites (p < 0.01). (4) The signal intensity was significantly higher using the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence around the dural sinus and ethmoid sinus (p < 0.001).

Conclusion

The 3D-T2-FLAIR sequence contrast-enhanced scan showed superior visualization of MLVs compared with the 3D-T2WI sequence.

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三维-T2WI 与三维-T2-FLAIR MRI 在显示人体脑膜淋巴管方面的比较研究。

目的：各种磁共振成像（MRI）序列可用于显示人体脑膜淋巴管（MLV），以研究MLV与中枢神经系统（CNS）疾病之间的关联。本研究旨在比较对比增强三维-T2WI和三维-T2-流体增强反转恢复（FLAIR）磁共振成像序列显示人体MLV的质量：结果：（1）3D-T2WI序列在硬脑膜窦、脑膜中动脉和乙状窦周围的阳性率分别为98.4%、29.0%和46.8%。3D-T2-FLAIR 序列的阳性率分别为 100%、48.4% 和 66.1%。在脑膜中动脉和乙状窦区域，3D-T2-FLAIR 序列的阳性率明显高于 3D-T2WI 序列（P < 0.05）。(2）在脑部病变和颅内占位性病变患者中，脑膜中动脉和乙状窦区域的 3D-T2-FLAIR 序列阳性率明显高于 3D-T2WI 序列（P < 0.05）。(3）在硬脑膜窦、脑膜中动脉和乙状窦周围，使用 3D-T2-FLAIR 序列与 3D-T2WI 序列相比，这三个部位的 MLV 平均横截面积均更高（P < 0.01）。(4）与 3D-T2WI 序列相比，硬膜窦和乙状窦周围的 3D-T2-FLAIR 序列信号强度明显更高（P < 0.001）：结论：与 3D-T2WI 序列相比，3D-T2-FLAIR 序列对比增强扫描显示 MLV 的可视化效果更佳。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical radiology 医学-核医学

CiteScore

4.70

自引率

3.80%

发文量

528

审稿时长

76 days

期刊介绍： Clinical Radiology is published by Elsevier on behalf of The Royal College of Radiologists. Clinical Radiology is an International Journal bringing you original research, editorials and review articles on all aspects of diagnostic imaging, including: • Computed tomography • Magnetic resonance imaging • Ultrasonography • Digital radiology • Interventional radiology • Radiography • Nuclear medicine Papers on radiological protection, quality assurance, audit in radiology and matters relating to radiological training and education are also included. In addition, each issue contains correspondence, book reviews and notices of forthcoming events.