Home blood pressure control and prescribing patterns of anti-hypertensive medications in a home blood pressure-based hypertension-specialized clinic in Japan: a sub-analysis of the Ohasama study.

IF 4.3 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE Hypertension Research Pub Date : 2024-10-28 DOI:10.1038/s41440-024-01954-7
Michihiro Satoh, Hirohito Metoki, Takahisa Murakami, Yukako Tatsumi, Kei Asayama, Masahiro Kikuya, Takayoshi Ohkubo, Yutaka Imai
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Abstract

Although the benefits of anti-hypertensive treatment are well known, the proportion of hypertensive patients with controlled blood pressure (BP) remains suboptimal. The present study aimed to compare BP control conditions in a hypertension-specialized clinic and non-hypertension-specialized clinics. This cross-sectional study used data from 379 treated patients who measured home BP in the Ohasama study between 2016 and 2019 (men: 43.0%, age: 71.6 years). Of those, 172 patients were managed at the hypertension-specialized clinic where physicians distributed home BP devices to each patient, evaluated the home BP data, and adjusted medications to maintain home BP values according to the recent Japanese guidelines. When we set morning home systolic/diastolic BP of <135/ < 85 mmHg as controlled BP, 93.6% of patients fulfilled the controlled home BP range, compared to 43.0% in non-specialized clinics (n = 207). The proportion of the patients with home morning BP < 125/ < 75 mmHg was 73.3% in the hypertension-specialized clinic and 20.8% in the non-hypertension-specialized clinics. Hypertension-specialized clinics prescribed three or more anti-hypertensive drug classes to 41.9% of patients, compared to 15.2% in non-specialized clinics. In the hypertension-specialized clinic, angiotensin II receptor blockers were most commonly prescribed (86.6%), followed by dihydropyridine calcium channel blockers (77.9%), thiazide (including thiazide-like) diuretics (30.2%), mineralocorticoid receptor blockers (23.8%), and beta- and alpha-beta blockers (10.5%). In conclusion, the proportion of patients with controlled home BP was excellent in the hypertension-specialized clinic. Home BP-based hypertension practices, as recommended in the current Japanese guidelines, may be the key to achieving sufficient BP control.

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日本以家庭血压为基础的高血压专科门诊的家庭血压控制和抗高血压药物处方模式:Ohasama 研究的子分析。
尽管抗高血压治疗的益处众所周知,但血压(BP)得到控制的高血压患者比例仍未达到最佳水平。本研究旨在比较高血压专科门诊和非高血压专科门诊的血压控制情况。这项横断面研究使用了2016年至2019年期间在Ohasama研究中测量家庭血压的379名接受治疗的患者的数据(男性:43.0%,年龄:71.6岁)。其中,172 名患者在高血压专科门诊接受了治疗,医生向每位患者分发了家庭血压仪,评估了家庭血压数据,并根据最新的日本指南调整药物以维持家庭血压值。当我们将早晨的家庭收缩压/舒张压设定为
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Hypertension Research
Hypertension Research 医学-外周血管病
CiteScore
7.40
自引率
16.70%
发文量
249
审稿时长
3-8 weeks
期刊介绍: Hypertension Research is the official publication of the Japanese Society of Hypertension. The journal publishes papers reporting original clinical and experimental research that contribute to the advancement of knowledge in the field of hypertension and related cardiovascular diseases. The journal publishes Review Articles, Articles, Correspondence and Comments.
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