Synthetic double inversion recovery imaging for rectal cancer T staging evaluation: imaging quality and added value to T2-weighted imaging.

IF 4.1 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Insights into Imaging Pub Date : 2024-10-24 DOI:10.1186/s13244-024-01796-4

Zi Wang, Zhuozhi Dai, Xinyi Zhou, Jiankun Dai, Yuxi Ge, Shudong Hu

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Abstract

Objective: To assess the image quality of synthetic double inversion recovery (SyDIR) imaging and enhance the value of T2-weighted imaging (T2WI) in evaluating T stage for rectal cancer patients.

Methods: A total of 112 pathologically confirmed rectal cancer patients were retrospectively selected after undergoing MRI, including synthetic MRI. The image quality of T2WI and SyDIR imaging was compared based on signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), overall picture quality, presence of motion artifacts, lesion edge sharpness, and conspicuity. The concordance between MRI and pathological staging results, using T2WI alone and the combination of T2WI and SyDIR for junior and senior radiologists, was assessed using the Kappa test. The area under the receiver operating characteristic curve (AUC) was used to assess the diagnostic efficacy of extramural infiltration in rectal cancer patients.

Results: No significant differences in imaging quality were observed between conventional T2WI and SyDIR (p = 0.07-0.53). The combination of T2WI and SyDIR notably improved the staging concordance between MRI and pathology for both junior (kappa value from 0.547 to 0.780) and senior radiologists (kappa value from 0.738 to 0.834). In addition, the integration of T2WI and SyDIR increased the AUC for diagnosing extramural infiltration for both junior (from 0.842 to 0.918) and senior radiologists (from 0.917 to 0.938).

Conclusion: The combination of T2WI and SyDIR increased the consistency of T staging between MRI and pathology, as well as the diagnostic performance of extramural infiltration, which would benefit treatment selection.

Critical relevance statement: SyDIR sequence provides additional diagnostic value for T2WI in the T staging of rectal cancer, improving the agreement of T staging between MRI and pathology, as well as the diagnostic performance of extramural infiltration.

Key points: Synthetic double inversion recovery (SyDIR) and T2WI have comparable image quality. SyDIR provides rectal cancer anatomical features for extramural infiltration detections. The combination of T2WI and SyDIR improves the accuracy of T staging in rectal cancer.

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用于直肠癌 T 分期评估的合成双反转恢复成像：成像质量和 T2 加权成像的附加值。

目的评估合成双反转恢复（SyDIR）成像的图像质量，提高 T2 加权成像（T2WI）在评估直肠癌患者 T 分期中的价值：方法：回顾性选取了112例经病理确诊的直肠癌患者进行磁共振成像（包括合成磁共振成像）检查。根据信噪比（SNR）、对比度与噪声比（CNR）、整体图像质量、运动伪影、病变边缘锐利度和清晰度，比较了T2WI和SyDIR成像的图像质量。对初级和高级放射科医生单独使用 T2WI 以及结合使用 T2WI 和 SyDIR 的 MRI 和病理分期结果的一致性采用 Kappa 检验进行评估。接受者操作特征曲线下面积（AUC）用于评估直肠癌患者硬膜外浸润的诊断效果：结果：传统 T2WI 和 SyDIR 的成像质量无明显差异（p = 0.07-0.53）。T2WI 和 SyDIR 的结合显著提高了初级放射医师（kappa 值从 0.547 到 0.780）和高级放射医师（kappa 值从 0.738 到 0.834）的 MRI 和病理分期一致性。此外，T2WI 和 SyDIR 的整合提高了初级放射医师（从 0.842 到 0.918）和高级放射医师（从 0.917 到 0.938）诊断硬膜外浸润的 AUC：结论：T2WI和SyDIR的结合提高了MRI和病理学T分期的一致性，也提高了对硬膜外浸润的诊断性能，这将有利于治疗选择：在直肠癌的T分期中，SyDIR序列为T2WI提供了额外的诊断价值，提高了MRI和病理学之间T分期的一致性以及硬膜外浸润的诊断性能：要点：合成双反转恢复（SyDIR）和 T2WI 的图像质量相当。要点：合成双倒置恢复（SyDIR）和 T2WI 的图像质量相当，SyDIR 可为硬膜外浸润检测提供直肠癌解剖学特征。T2WI 和 SyDIR 的结合提高了直肠癌 T 分期的准确性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Insights into Imaging Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

7.30

自引率

4.30%

发文量

182

审稿时长

13 weeks

期刊介绍： Insights into Imaging (I³) is a peer-reviewed open access journal published under the brand SpringerOpen. All content published in the journal is freely available online to anyone, anywhere! I³ continuously updates scientific knowledge and progress in best-practice standards in radiology through the publication of original articles and state-of-the-art reviews and opinions, along with recommendations and statements from the leading radiological societies in Europe. Founded by the European Society of Radiology (ESR), I³ creates a platform for educational material, guidelines and recommendations, and a forum for topics of controversy. A balanced combination of review articles, original papers, short communications from European radiological congresses and information on society matters makes I³ an indispensable source for current information in this field. I³ is owned by the ESR, however authors retain copyright to their article according to the Creative Commons Attribution License (see Copyright and License Agreement). All articles can be read, redistributed and reused for free, as long as the author of the original work is cited properly. The open access fees (article-processing charges) for this journal are kindly sponsored by ESR for all Members. The journal went open access in 2012, which means that all articles published since then are freely available online.