Drugs used in psychiatry causing an increase in body weight in children-a review.

IF 4.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM International Journal of Obesity Pub Date : 2024-10-24 DOI:10.1038/s41366-024-01662-9
Karolina Kuźbicka, Iga Pawłowska, Ivan Kocić
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Abstract

Body weight gain is a prevalent adverse effect observed in psychiatric medication therapy. With the notable increase in mental health diagnoses among children and adolescents over the last decade, exacerbated by the COVID-19 pandemic, the use of medications associated with weight gain poses an additional risk for obesity development. This study aimed to identify psychiatric drugs that may induce weight gain in children as a side effect. Twenty-nine publications were included in this systematic review, investigating the effects of nineteen different drugs on children's weight. The majority of these drugs belonged to atypical antipsychotics and anticonvulsants. Nearly all included articles reported that the examined substances resulted in weight gain in children. As childhood obesity has become a significant problem with various metabolic, psychological and social consequences, it is crucial to carefully consider therapy options. In addition to evaluating effectiveness, it is important to also assess the potential for weight gain. Clinicians and nutrition specialists should individually evaluate patients' nutritional needs, evaluate obesity risk, and provide appropriate dietary guidance to minimalize the risk of weight gain.

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导致儿童体重增加的精神科用药--综述。
体重增加是精神科药物治疗中普遍存在的不良反应。在过去十年中,儿童和青少年的精神健康诊断显著增加,COVID-19 的流行更加剧了这一趋势,因此使用与体重增加相关的药物会增加肥胖的风险。本研究旨在找出可能导致儿童体重增加的精神科药物副作用。本系统综述共收录了 29 篇文献,调查了 19 种不同药物对儿童体重的影响。这些药物大多属于非典型抗精神病药物和抗惊厥药物。几乎所有收录的文章都报告说,所研究的药物会导致儿童体重增加。由于儿童肥胖症已成为一个严重问题,会造成各种代谢、心理和社会后果,因此仔细考虑治疗方案至关重要。除了评估有效性外,还必须评估体重增加的可能性。临床医生和营养专家应单独评估患者的营养需求,评估肥胖风险,并提供适当的饮食指导,将体重增加的风险降至最低。
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来源期刊
International Journal of Obesity
International Journal of Obesity 医学-内分泌学与代谢
CiteScore
10.00
自引率
2.00%
发文量
221
审稿时长
3 months
期刊介绍: The International Journal of Obesity is a multi-disciplinary forum for research describing basic, clinical and applied studies in biochemistry, physiology, genetics and nutrition, molecular, metabolic, psychological and epidemiological aspects of obesity and related disorders. We publish a range of content types including original research articles, technical reports, reviews, correspondence and brief communications that elaborate on significant advances in the field and cover topical issues.
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