Osteochondral Autograft Transplantation for Symptomatic Full-thickness Patellar Cartilage Defects in Adolescents.

IF 1.4 3区 医学 Q3 ORTHOPEDICS Journal of Pediatric Orthopaedics Pub Date : 2024-10-24 DOI:10.1097/BPO.0000000000002850
Javier Masquijo, Miguel Carabajal Mattar, Alejandra Ron Marqués, Alberto Losa, Juan Cabello Blanco, Joaquín Nuñez de Armas, Maria J Tuca
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Abstract

Background: This study aimed to review the clinical, radiographic, and magnetic resonance imaging (MRI) outcomes of osteochondral autograft transplantation applied to patellar cartilage lesions of patients under 18 years of age.

Methods: Data from nine consecutive patients were retrospectively analyzed for indications, preoperative complications, and clinical-radiographic outcomes. Patients were clinically evaluated using the Pedi-IKDC and Lysholm scores. In addition, return to sports and knee pain were assessed. MRI evaluation included an analysis of osteochondral graft integration using the magnetic resonance observation of cartilage repair tissue 2.0 score and radiographic classification of osteoarthritis using the Kellgren-Lawrence system.

Results: Nine patients (9 knees, 6 males) with a mean age of 14 years (SD: 1.7, range; 11 to 17 y) were analyzed. Lesions were located on the medial facet (N=5), lateral facet (N=3), and central ridge of the patella (N=1). One or 2 cylindrical osteochondral grafts were transplanted, with a median diameter of 9 mm (range: 8 to 10 mm). The average lesion size was 102.9 mm2. At a mean follow-up of 45.1 months (range: 23 to 117 mo), the mean Pedi-IKDC score was 89.2 (SD: 9.8), and the Lysholm score was 94.4 (SD: 4.8). Patients returned to sports in an average of 7.3 months (SD: 2, range: 6 to 12 mo). MRI of 8 patients showed osteochondral graft integration with a mean magnetic resonance observation of cartilage repair tissue 2.0 score of 86.9 (SD: 7, range: 80 to 100). Six knees showed Kellgren-Lawrence grade 0 joint space on radiographs, and 3 showed grade 1. Eight patients were asymptomatic at the last follow-up, and 1 reported occasional mild pain with intense physical activity. One patient developed arthrofibrosis, requiring arthroscopic lysis of adhesions and manipulation.

Conclusion: Osteochondral autograft transplantation is a safe and effective technique for treating symptomatic patellar full-thickness chondral lesions in adolescents. Long-term follow-up studies will determine whether the affected area maintains structural and functional integrity over time.

Level of evidence: Level IV-therapeutic study.

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骨软骨自体移植治疗青少年症状性全厚髌骨软骨缺损。
背景:本研究旨在回顾18岁以下患者髌骨软骨病变应用骨软骨自体移植的临床、影像学和磁共振成像(MRI)结果:对九名连续患者的适应症、术前并发症和临床放射成像结果进行了回顾性分析。使用 Pedi-IKDC 和 Lysholm 评分对患者进行临床评估。此外,还对运动恢复情况和膝关节疼痛进行了评估。磁共振成像评估包括使用软骨修复组织磁共振观察2.0评分分析骨软骨移植的整合情况,以及使用Kellgren-Lawrence系统对骨关节炎进行放射学分类:分析了九名患者(九个膝盖,六名男性),他们的平均年龄为 14 岁(SD:1.7,范围:11 至 17 岁)。病变位于髌骨内侧面(5 例)、外侧面(3 例)和中央脊(1 例)。移植了一个或两个圆柱形骨软骨移植物,中位直径为9毫米(范围:8至10毫米)。平均病变面积为 102.9 平方毫米。平均随访45.1个月(23至117个月),Pedi-IKDC平均评分为89.2(标清:9.8),Lysholm评分为94.4(标清:4.8)。患者平均在 7.3 个月(标准差:2,范围:6 至 12 个月)后恢复运动。8名患者的磁共振成像显示骨软骨移植融合,软骨修复组织2.0磁共振观察平均得分86.9(标度:7,范围:80至100)。6个膝关节的X光片显示凯尔格伦-劳伦斯(Kellgren-Lawrence)关节间隙为0级,3个为1级。8 名患者在最后一次随访时无症状,1 名患者在剧烈运动时偶尔会出现轻微疼痛。一名患者出现关节纤维化,需要在关节镜下进行粘连溶解和操作:结论:骨软骨自体移植是治疗青少年无症状髌骨全厚软骨损伤的一种安全有效的技术。长期随访研究将确定患处是否能长期保持结构和功能的完整性:证据等级:IV 级--治疗研究。
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来源期刊
CiteScore
3.30
自引率
17.60%
发文量
512
审稿时长
6 months
期刊介绍: ​Journal of Pediatric Orthopaedics is a leading journal that focuses specifically on traumatic injuries to give you hands-on on coverage of a fast-growing field. You''ll get articles that cover everything from the nature of injury to the effects of new drug therapies; everything from recommendations for more effective surgical approaches to the latest laboratory findings.
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