Sameer Gupta MD, MPhil , Michael Shaughnessy MD , Sarem Rashid BS , Anna M. Stagner MD , Jessica Fewkes MD , Ashfaq A. Marghoob MD , Hensin Tsao MD, PhD
{"title":"Lentigo maligna part II: Management","authors":"Sameer Gupta MD, MPhil , Michael Shaughnessy MD , Sarem Rashid BS , Anna M. Stagner MD , Jessica Fewkes MD , Ashfaq A. Marghoob MD , Hensin Tsao MD, PhD","doi":"10.1016/j.jaad.2024.07.1534","DOIUrl":null,"url":null,"abstract":"<div><div>Lentigo maligna arises on chronically-sun damaged skin and can have extensive subclinical spread, often in functionally and cosmetically challenging areas. This two-part continuing medical education series reviews lentigo maligna. Part I reviews epidemiology, risk factors, clinical presentation, diagnostic tools, biopsy technique, and histopathology of lentigo maligna. Part II reviews both surgical and nonsurgical treatment options. Surgical approaches – including conventional excision, Mohs micrographic surgery, and staged excision – remain first-line therapy to achieve cure. Some patients may be poor surgical candidates or elect for alternative treatments. Nonsurgical modalities, such as topical and radiation therapy, are also reviewed. Finally, surveillance recommendations are discussed.</div></div>","PeriodicalId":17198,"journal":{"name":"Journal of the American Academy of Dermatology","volume":"93 6","pages":"Pages 1399-1410"},"PeriodicalIF":11.8000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the American Academy of Dermatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0190962224030093","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/22 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Lentigo maligna arises on chronically-sun damaged skin and can have extensive subclinical spread, often in functionally and cosmetically challenging areas. This two-part continuing medical education series reviews lentigo maligna. Part I reviews epidemiology, risk factors, clinical presentation, diagnostic tools, biopsy technique, and histopathology of lentigo maligna. Part II reviews both surgical and nonsurgical treatment options. Surgical approaches – including conventional excision, Mohs micrographic surgery, and staged excision – remain first-line therapy to achieve cure. Some patients may be poor surgical candidates or elect for alternative treatments. Nonsurgical modalities, such as topical and radiation therapy, are also reviewed. Finally, surveillance recommendations are discussed.
期刊介绍:
The Journal of the American Academy of Dermatology (JAAD) is the official scientific publication of the American Academy of Dermatology (AAD). Its primary goal is to cater to the educational requirements of the dermatology community. Being the top journal in the field, JAAD publishes original articles that have undergone peer review. These articles primarily focus on clinical, investigative, and population-based studies related to dermatology. Another key area of emphasis is research on healthcare delivery and quality of care. JAAD also highlights high-quality, cost-effective, and innovative treatments within the field. In addition to this, the journal covers new diagnostic techniques and various other topics relevant to the prevention, diagnosis, and treatment of skin, hair, and nail disorders.