Edan Jackson, Josh Li, Thilini Weerasinghe, Xin Li
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引用次数: 0
Abstract
Fusarium oxysporum is one of the most economically important plant fungal pathogens, causing devastating Fusarium wilt diseases on a diverse range of hosts, including many key crop plants. Consequently, F. oxysporum has been the subject of extensive research to help develop and improve crop protection strategies. The sequencing of the F. oxysporum genome 14 years ago has greatly accelerated the discovery and characterization of key genes contributing to F. oxysporum biology and virulence. In this review, we summarize important findings on the molecular mechanisms of F. oxysporum growth, reproduction, and virulence. In particular, we focus on genes studied through mutant analysis, covering genes involved in diverse processes such as metabolism, stress tolerance, sporulation, and pathogenicity, as well as the signaling pathways that regulate them. In doing so, we hope to present a comprehensive review of the molecular understanding of F. oxysporum that will aid the future study of this and related species.
镰孢菌（Fusarium oxysporum）是最具经济价值的植物真菌病原体之一，可对多种寄主（包括许多主要农作物）造成毁灭性的镰孢枯萎病。因此，F. oxysporum 一直是广泛研究的主题，以帮助开发和改进作物保护策略。14 年前对 F. oxysporum 基因组的测序大大加快了对 F. oxysporum 生物学和毒力关键基因的发现和鉴定。在这篇综述中，我们总结了有关 F. oxysporum 生长、繁殖和毒力分子机制的重要发现。我们尤其关注通过突变体分析研究的基因，涵盖涉及代谢、抗逆性、孢子和致病性等不同过程的基因，以及调控这些基因的信号通路。我们希望通过这些研究，全面回顾对 F. oxysporum 的分子认识，从而有助于今后对该物种及相关物种的研究。
期刊介绍：
Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.
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