The basic statistical concepts and their interrelationships in diagnostic research.

IF 2.7 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Postgraduate Medical Journal Pub Date : 2025-02-19 DOI:10.1093/postmj/qgae139
Yitao Mao, Juxiong Xiao, Liping Zhu, Yu Zhang, Yueshuang Leng, Qingling Li, Ying Li, Chuyi Liu, Luqing Zhao
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Abstract

Background: Many medical postgraduate students exhibit a lack of clarity in their understanding of relevant statistical concepts during the conduct of diagnostic studies.

Methods: This article, grounded in research practice, delves into the role of understanding statistical concepts in diagnostic research. It includes an exploration of sensitivity, specificity, types of statistical errors, and their interrelationships, as well as a discussion on statistical power-an often-overlooked but crucial concept in research.

Results: The article elucidates these important concepts with specific examples and illustrations, and addresses an issue of inconsistency related to the receiver operating characteristic curve in research practice.

Conclusion: By drawing analogies between basic concepts in diagnostic tests and concepts in statistics, this article helps to enhance researchers' abilities in designing and interpreting clinical diagnostic studies, thereby improving the quality of clinical diagnostic research.

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诊断研究中的基本统计概念及其相互关系。
背景:许多医学研究生在进行诊断研究时,对相关统计概念的理解不够清晰:本文立足于研究实践,深入探讨了理解统计学概念在诊断研究中的作用。其中包括对灵敏度、特异性、统计误差类型及其相互关系的探讨,以及对统计能力的讨论--这是研究中经常被忽视但却至关重要的概念:文章通过具体的例子和说明阐明了这些重要概念,并解决了研究实践中与接收者操作特征曲线相关的不一致问题:本文通过类比诊断测试中的基本概念和统计学中的概念,有助于提高研究人员设计和解释临床诊断研究的能力,从而提高临床诊断研究的质量。
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来源期刊
Postgraduate Medical Journal
Postgraduate Medical Journal 医学-医学:内科
CiteScore
8.50
自引率
2.00%
发文量
131
审稿时长
2.5 months
期刊介绍: Postgraduate Medical Journal is a peer reviewed journal published on behalf of the Fellowship of Postgraduate Medicine. The journal aims to support junior doctors and their teachers and contribute to the continuing professional development of all doctors by publishing papers on a wide range of topics relevant to the practicing clinician and teacher. Papers published in PMJ include those that focus on core competencies; that describe current practice and new developments in all branches of medicine; that describe relevance and impact of translational research on clinical practice; that provide background relevant to examinations; and papers on medical education and medical education research. PMJ supports CPD by providing the opportunity for doctors to publish many types of articles including original clinical research; reviews; quality improvement reports; editorials, and correspondence on clinical matters.
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