Establishment of an induced pluripotent stem cell line (SDCHi011-A) from a healthy Chinese female donor

IF 0.8 4区 医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Stem cell research Pub Date : 2024-10-19 DOI:10.1016/j.scr.2024.103588
Shuyun Wang , Qian Zeng , Mengmeng Chen , Haiyan Zhang , Xin Lv
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引用次数: 0

Abstract

We generated an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) of a healthy 40-year-old Chinese Han female, using non-integrated reprogramming technology. The established iPSC line, SDCHi011-A, expressed pluripotency marker and could differentiate into cells of three germ layers in vitro with normal karyotype. This cell line is a valuable resource as a control line for stem cell research of disease models and molecular pathogenesis.
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从一名健康的中国女性供体中建立诱导多能干细胞系(SDCHi011-A)。
我们利用非整合重编程技术,从一名 40 岁健康中国汉族女性的外周血单核细胞(PBMC)中生成了一个诱导多能干细胞(iPSC)系。建立的 iPSC 细胞系 SDCHi011-A 表达了多能性标记,可在体外分化为三个生殖层的细胞,核型正常。该细胞系是疾病模型和分子发病机制干细胞研究的宝贵对照系资源。
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来源期刊
Stem cell research
Stem cell research 生物-生物工程与应用微生物
CiteScore
2.20
自引率
8.30%
发文量
338
审稿时长
55 days
期刊介绍: Stem Cell Research is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. Submissions to Stem Cell Research, may cover all aspects of stem cells, including embryonic stem cells, tissue-specific stem cells, cancer stem cells, developmental studies, stem cell genomes, and translational research. Stem Cell Research publishes 6 issues a year.
期刊最新文献
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