Optimization and Protection of Kidney Health in Liver Transplant Recipients: Intra- and Postoperative Approaches.

IF 5.3 2区 医学 Q1 IMMUNOLOGY Transplantation Pub Date : 2024-10-23 DOI:10.1097/TP.0000000000005252
Muhammad Y Jan, Kavish R Patidar, Marwan S Ghabril, Chandrashekhar A Kubal
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Abstract

Postoperative acute kidney injury after liver transplant (LT) has long-term implications for kidney health. LT recipients are at risk of acute kidney injury due to a number of factors related to the donor liver, intraoperative factors including surgical technique, as well as recipient factors, such as pre-LT kidney function and postoperative complications. This review discusses these factors in detail and their impact on posttransplant kidney function. Long-term risk factors such as calcineurin inhibitors have also been discussed. Additionally, the impact of liver allocation policies on pre- and post-LT kidney health is discussed.

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优化和保护肝移植受者的肾脏健康:术中和术后方法。
肝移植(LT)术后急性肾损伤对肾脏健康有长期影响。肝移植受者面临急性肾损伤风险的原因有很多,包括与供肝有关的因素、包括手术技术在内的术中因素以及受者因素,如肝移植前的肾功能和术后并发症。本综述将详细讨论这些因素及其对移植后肾功能的影响。此外,还讨论了钙神经蛋白抑制剂等长期风险因素。此外,还讨论了肝脏分配政策对移植前和移植后肾脏健康的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Transplantation
Transplantation 医学-免疫学
CiteScore
8.50
自引率
11.30%
发文量
1906
审稿时长
1 months
期刊介绍: The official journal of The Transplantation Society, and the International Liver Transplantation Society, Transplantation is published monthly and is the most cited and influential journal in the field, with more than 25,000 citations per year. Transplantation has been the trusted source for extensive and timely coverage of the most important advances in transplantation for over 50 years. The Editors and Editorial Board are an international group of research and clinical leaders that includes many pioneers of the field, representing a diverse range of areas of expertise. This capable editorial team provides thoughtful and thorough peer review, and delivers rapid, careful and insightful editorial evaluation of all manuscripts submitted to the journal. Transplantation is committed to rapid review and publication. The journal remains competitive with a time to first decision of fewer than 21 days. Transplantation was the first in the field to offer CME credit to its peer reviewers for reviews completed. The journal publishes original research articles in original clinical science and original basic science. Short reports bring attention to research at the forefront of the field. Other areas covered include cell therapy and islet transplantation, immunobiology and genomics, and xenotransplantation. ​
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