[A Case of Drug-Induced Lung Injury That Developed the Day after Abemaciclib Treatment for Advanced Breast Cancer].

Q4 Medicine Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-09-01
Mikiko Kai, Yumiko Taki, Akiko Ikeda, Tatsuya Igarashi, Satoshi Hasegawa
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引用次数: 0

Abstract

A 74-year-old woman was diagnosed with invasive breast ductal carcinoma, cT2N0M1 (PUL), stage Ⅳ, and treated with abemaciclib and letrozole. The day after drug administration, the patient developed a fever of 38℃ and dyspnea upon exertion, and was diagnosed with drug-induced pneumonia. Steroid pulse therapy was administered during hospitalization, and the patient was discharged after the dose of prednisolone was gradually reduced. This case shows that, when abemaciclib is administered, drug-induced lung injury can occur within 1 week.

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[晚期乳腺癌 Abemaciclib 治疗后第二天出现的药物诱发肺损伤病例]。
一名74岁的女性患者被诊断为浸润性乳腺导管癌,cT2N0M1(PUL),Ⅳ期,并接受了阿贝昔单抗和来曲唑治疗。用药后第二天,患者出现发热 38℃和呼吸困难,被诊断为药物性肺炎。住院期间给予了类固醇脉冲治疗,患者在逐渐减少泼尼松龙剂量后出院。该病例表明,服用阿贝昔单抗后,可在一周内发生药物性肺损伤。
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