Intravenous Leiomyomatosis of the Uterus: An Intriguing Case Revealed through Anatomopathological Examination.

Q3 Medicine Tunisie Medicale Pub Date : 2024-10-05 DOI:10.62438/tunismed.v102i10.5139
Khaoula Magdoud, Abir Karoui, Nadia Boujelbene, Rim Ben Hmid
{"title":"Intravenous Leiomyomatosis of the Uterus: An Intriguing Case Revealed through Anatomopathological Examination.","authors":"Khaoula Magdoud, Abir Karoui, Nadia Boujelbene, Rim Ben Hmid","doi":"10.62438/tunismed.v102i10.5139","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Intravenous leiomyomatosis (IVL), a rare type of uterine leiomyoma (its incidence is about 0.25% to 0.40% of patients who present uterine fibroma), is characterized by the formation and growth of benign leiomyoma tissue within the vascular wall or lymphatic lumen. Herein, we presented a case of early stage of IVL successfully treated by surgical removal and a review of actual medical recommendations.</p><p><strong>Observation: </strong>A 49-year-old woman, gravida 2 para 2, presented to our department with hypogastric pain. On physical examination, a palpable mass in the hypogastrium was noted. Pelvic ultrasound showed a huge uterus with multiple heterogeneous leiomyomas. As the patient was symptomatic and as she had completed their family plan, the decision to perform a total abdominal hysterectomy with bilateral salpingo-oophorectomy was taken. On pathological examination, intravascular growth of benign smooth muscle cell was found within venous channels lined by endothelium. The diagnosis of IVL of the uterus without malignant transformation was confirmed. The patient was monitored for 14 months, and subsequent computed tomography did not reveal any evidence of tumor recurrence.</p><p><strong>Conclusion: </strong>IVL is a benign, rare and potentially lethal pathology. Clinical manifestations are nonspecific. IVL needs surgical treatment for diagnosis and therapeutic purposes. They require close and prolonged follow-up because of the high risk of recurrence.</p>","PeriodicalId":38818,"journal":{"name":"Tunisie Medicale","volume":"102 10","pages":"722-724"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574368/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tunisie Medicale","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.62438/tunismed.v102i10.5139","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Intravenous leiomyomatosis (IVL), a rare type of uterine leiomyoma (its incidence is about 0.25% to 0.40% of patients who present uterine fibroma), is characterized by the formation and growth of benign leiomyoma tissue within the vascular wall or lymphatic lumen. Herein, we presented a case of early stage of IVL successfully treated by surgical removal and a review of actual medical recommendations.

Observation: A 49-year-old woman, gravida 2 para 2, presented to our department with hypogastric pain. On physical examination, a palpable mass in the hypogastrium was noted. Pelvic ultrasound showed a huge uterus with multiple heterogeneous leiomyomas. As the patient was symptomatic and as she had completed their family plan, the decision to perform a total abdominal hysterectomy with bilateral salpingo-oophorectomy was taken. On pathological examination, intravascular growth of benign smooth muscle cell was found within venous channels lined by endothelium. The diagnosis of IVL of the uterus without malignant transformation was confirmed. The patient was monitored for 14 months, and subsequent computed tomography did not reveal any evidence of tumor recurrence.

Conclusion: IVL is a benign, rare and potentially lethal pathology. Clinical manifestations are nonspecific. IVL needs surgical treatment for diagnosis and therapeutic purposes. They require close and prolonged follow-up because of the high risk of recurrence.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
子宫静脉内雷肌瘤病:通过解剖病理学检查发现的一个耐人寻味的病例
导言:静脉内子宫肌瘤病(IVL)是一种罕见的子宫肌瘤类型(其发病率约为子宫肌瘤患者的 0.25% 至 0.40%),其特点是良性子宫肌瘤组织在血管壁或淋巴管腔内形成和生长。在此,我们介绍了一例通过手术切除成功治疗的 IVL 早期病例,并回顾了实际的医疗建议:一名 49 岁的妇女,孕 2 期 2 段,因下腹疼痛来我科就诊。体格检查时发现下腹部可触及肿块。盆腔超声波检查显示患者子宫巨大,并伴有多发性异型子宫肌瘤。由于患者无症状,且已完成家庭计划,因此决定进行全腹子宫切除术和双侧输卵管切除术。病理检查发现,良性平滑肌细胞在血管内皮衬里的静脉通道内生长。确诊为子宫 IVL,无恶变。患者接受了 14 个月的监测,随后的计算机断层扫描没有发现任何肿瘤复发的迹象:结论:IVL 是一种良性、罕见且可能致命的病变。临床表现无特异性。IVL 的诊断和治疗需要外科手术。由于复发的风险很高,因此需要进行密切和长期的随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Tunisie Medicale
Tunisie Medicale Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
72
期刊最新文献
Ethics and Practices of the Pharmacist. Evaluation of learning abilities after role-playing method: Comparing outcomes of Active and Observer. From Thesis to Publication: Unveiling the Predictive Factors for Cardiology Research at a North African Faculty of Medicine (Tunisia). Impact of therapeutic education on quality of life in coronary patients: Interventional study. Impacts of zinc enriched spirulina as an adjunct to conventional treatment of patients with Chronic Obstructive Pulmonary Disease: Study protocol for a North African randomized controlled trial (SPIRICOPD).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1