Harnessing the Power of Fermented Tea to Improve Gut Microbiota and Combat Obesity Epidemic.

IF 3.6 3区 生物学 Q1 BIOLOGY Biology-Basel Pub Date : 2024-09-28 DOI:10.3390/biology13100779
Ruyi Zhang, Qiling Li, Yuxuan Gu, Wenli Liao
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Abstract

The global rise in obesity rates has prompted a thorough evaluation of dietary strategies that may alleviate this metabolic issue. Fermented tea, a beverage rich in polyphenols and catechins, has emerged as a viable therapeutic option for obesity management. This review discusses the role of fermented tea in modulating the gut microbiome, a critical factor in energy regulation and obesity. We explore how the bioactive components in fermented tea influence gut health and their implications for metabolic health. Fermented tea may inhibit weight gain and fat accumulation in obese animal models, likely by promoting beneficial bacteria and suppressing harmful species. Changes in the production of short-chain fatty acids and improvements in gut barrier integrity are linked to enhanced insulin sensitivity and reduced inflammatory markers, essential for effective obesity management. However, barriers remain in applying these findings in clinical settings, such as the need for standardized fermentation techniques and accurate dosage assessments. This review underscores the therapeutic potential of fermented tea in obesity treatment and advocates for further research to enhance its integration with public health initiatives.

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利用发酵茶的力量改善肠道微生物群,应对肥胖症流行。
全球肥胖率的上升促使人们对可缓解这一代谢问题的饮食策略进行全面评估。发酵茶是一种富含茶多酚和儿茶素的饮料,已成为肥胖症控制的可行治疗方案。本综述讨论了发酵茶在调节肠道微生物组方面的作用,肠道微生物组是能量调节和肥胖的关键因素。我们探讨了发酵茶中的生物活性成分如何影响肠道健康及其对代谢健康的影响。发酵茶可抑制肥胖动物模型的体重增加和脂肪积累,这可能是通过促进有益菌群和抑制有害菌群实现的。短链脂肪酸产生的变化和肠道屏障完整性的改善与胰岛素敏感性的提高和炎症标志物的减少有关,这对有效控制肥胖至关重要。然而,将这些发现应用于临床仍然存在障碍,例如需要标准化的发酵技术和准确的剂量评估。这篇综述强调了发酵茶在肥胖症治疗中的治疗潜力,并提倡进一步开展研究,以加强发酵茶与公共卫生措施的结合。
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来源期刊
Biology-Basel
Biology-Basel Biological Science-Biological Science
CiteScore
5.70
自引率
4.80%
发文量
1618
审稿时长
11 weeks
期刊介绍: Biology (ISSN 2079-7737) is an international, peer-reviewed, quick-refereeing open access journal of Biological Science published by MDPI online. It publishes reviews, research papers and communications in all areas of biology and at the interface of related disciplines. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files regarding the full details of the experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
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