The emerging role of Never-in-Mitosis A - Related Kinases in the endothelium

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-10-24 DOI:10.1016/j.biocel.2024.106679
Nektarios Barabutis, Saikat Fakir
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引用次数: 0

Abstract

The endothelium forms a monolayer, which functions to ensure tissue homeostasis. Barrier hyperpermeability has been associated with lung, brain and eye disease. An emerging body of evidence reports the involvement of Never-in-Mitosis A - Related Kinases in vascular responses, suggesting their value as potential therapeutic targets in endothelial-dependent disorders.
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内皮细胞中从未蜕变的 A 相关激酶的新作用
内皮形成一个单层,具有确保组织稳态的功能。屏障高渗透性与肺、脑和眼部疾病有关。越来越多的证据表明,与内皮细胞有关的 A 型激酶参与了血管反应,这表明它们作为内皮依赖性疾病的潜在治疗靶点具有潜在价值。
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
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