Theranostics, Advanced Cancer, and The Meaning of Life.

IF 2.4 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Cancer Biotherapy and Radiopharmaceuticals Pub Date : 2024-12-01 Epub Date: 2024-10-22 DOI:10.1089/cbr.2024.0176
J Harvey Turner
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Abstract

There is an unmet need to recognize and address the psychosocial and spiritual support of the rapidly growing population of cancer survivors living with advanced metastatic disease which is essentially incurable. Palliative chemotherapy may do more harm than good. The role of the physician in the provision of a supportive, compassionate relationship of mutual trust is critical in the exploration of spirituality and the meaning of life for each individual patient. The objective must be to enhance quality of life rather than prolong it at any cost. Nuclear physicians are now equipped to offer effective control of advanced metastatic cancer of prostate and neuroendocrine neoplasms without clinically evident toxicity. They also now have the potential to practice phronesis, and in so doing, to significantly ameliorate the quality of life of patients afflicted with these specific advanced cancers. During the time of prolonged symptom-free survival, these patients may be encouraged to find life's meaning and a peaceful acceptance of their inevitable demise.

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疗法、晚期癌症和生命的意义。
对于迅速增长的晚期转移性疾病癌症幸存者来说,他们的社会心理和精神支持基本上是无法治愈的,而这一需求尚未得到满足。姑息化疗可能弊大于利。医生在提供相互信任、富有同情心的支持性关系方面所扮演的角色,对于探索每位患者的精神世界和生命意义至关重要。目标必须是提高生活质量,而不是不惜一切代价延长生命。核医生现在有能力有效控制晚期转移性前列腺癌和神经内分泌肿瘤,而不会产生明显的临床毒性。他们现在也有可能实行 "phronesis "疗法,从而显著改善这些特定晚期癌症患者的生活质量。在无症状生存期延长期间,可以鼓励这些患者找到生命的意义,平静地接受自己不可避免的死亡。
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来源期刊
CiteScore
7.80
自引率
2.90%
发文量
87
审稿时长
3 months
期刊介绍: Cancer Biotherapy and Radiopharmaceuticals is the established peer-reviewed journal, with over 25 years of cutting-edge content on innovative therapeutic investigations to ultimately improve cancer management. It is the only journal with the specific focus of cancer biotherapy and is inclusive of monoclonal antibodies, cytokine therapy, cancer gene therapy, cell-based therapies, and other forms of immunotherapies. The Journal includes extensive reporting on advancements in radioimmunotherapy, and the use of radiopharmaceuticals and radiolabeled peptides for the development of new cancer treatments.
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