Functional quantile principal component analysis.

IF 1.8 3区 数学 Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY Biostatistics Pub Date : 2024-10-23 DOI:10.1093/biostatistics/kxae040
Álvaro Méndez-Civieta, Ying Wei, Keith M Diaz, Jeff Goldsmith
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Abstract

This paper introduces functional quantile principal component analysis (FQPCA), a dimensionality reduction technique that extends the concept of functional principal components analysis (FPCA) to the examination of participant-specific quantiles curves. Our approach borrows strength across participants to estimate patterns in quantiles, and uses participant-level data to estimate loadings on those patterns. As a result, FQPCA is able to capture shifts in the scale and distribution of data that affect participant-level quantile curves, and is also a robust methodology suitable for dealing with outliers, heteroscedastic data or skewed data. The need for such methodology is exemplified by physical activity data collected using wearable devices. Participants often differ in the timing and intensity of physical activity behaviors, and capturing information beyond the participant-level expected value curves produced by FPCA is necessary for a robust quantification of diurnal patterns of activity. We illustrate our methods using accelerometer data from the National Health and Nutrition Examination Survey, and produce participant-level 10%, 50%, and 90% quantile curves over 24 h of activity. The proposed methodology is supported by simulation results, and is available as an R package.

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功能量化主成分分析
本文介绍了功能量化主成分分析(FQPCA),这是一种降维技术,它将功能主成分分析(FPCA)的概念扩展到了对特定参与者量化曲线的研究。我们的方法借用不同参与者的力量来估计量化曲线的模式,并使用参与者层面的数据来估计这些模式的载荷。因此,FQPCA 能够捕捉到数据规模和分布中影响参与者水平量化曲线的变化,也是一种适用于处理异常值、异方差数据或倾斜数据的稳健方法。使用可穿戴设备收集的身体活动数据就说明了对这种方法的需求。参与者的体力活动行为在时间和强度上往往各不相同,要想对昼夜活动模式进行稳健的量化,就必须捕捉 FPCA 生成的参与者级预期值曲线以外的信息。我们使用美国国家健康与营养调查的加速度计数据来说明我们的方法,并生成了参与者水平的 10%、50% 和 90% 的 24 小时活动量定量曲线。我们提出的方法得到了模拟结果的支持,并以 R 软件包的形式提供。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biostatistics
Biostatistics 生物-数学与计算生物学
CiteScore
5.10
自引率
4.80%
发文量
45
审稿时长
6-12 weeks
期刊介绍: Among the important scientific developments of the 20th century is the explosive growth in statistical reasoning and methods for application to studies of human health. Examples include developments in likelihood methods for inference, epidemiologic statistics, clinical trials, survival analysis, and statistical genetics. Substantive problems in public health and biomedical research have fueled the development of statistical methods, which in turn have improved our ability to draw valid inferences from data. The objective of Biostatistics is to advance statistical science and its application to problems of human health and disease, with the ultimate goal of advancing the public''s health.
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