Siyi Wang, Longyu Wang, Jiaolei Shangguan, Ailiang Jiang, Ang Ren
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引用次数: 0
Abstract
Ganoderma lucidum (G. lucidum) is a traditional edible and medicinal mushroom in China. The main bioactive components in G. lucidum include triterpenoids, polysaccharides, steroids, and sterols. Ganoderic acids (GAs) are one of the most abundant triterpenoids found in G. lucidum, garnering significant attention from researchers in the fields of medicine and health care. We summarize the extensive studies on the physiological function of GAs in anti-cancer, anti-inflammatory, radiation protection, anti-aging, liver protection, anti-microbial, and neuroprotection areas, among others. This review provides a comprehensive overview of the recent advances in the bioactivities and pharmacological mechanisms of GAs, aiming to delineate the current research directions and the state of the art in this field. This analysis helps to rapidly identify new bioactivities of GAs and understand their mechanisms, leading to more effective treatments for various diseases.
灵芝（Ganoderma lucidum）是中国传统的食用和药用菌。灵芝中的主要生物活性成分包括三萜类、多糖、类固醇和甾醇。灵芝酸（Ganoderic acids，GAs）是灵芝中发现的最丰富的三萜类化合物之一，受到医学和保健领域研究人员的极大关注。我们总结了有关 GAs 在抗癌、抗炎、防辐射、抗衰老、保肝、抗微生物和神经保护等方面生理功能的大量研究。这篇综述全面概述了最近在 GAs 的生物活性和药理机制方面取得的进展，旨在勾勒出该领域当前的研究方向和技术水平。这种分析有助于快速确定 GAs 的新生物活性并了解其机制，从而更有效地治疗各种疾病。
Life-BaselBiochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
4.30
自引率
6.20%
发文量
1798
审稿时长
11 weeks
期刊介绍：
Life (ISSN 2075-1729) is an international, peer-reviewed open access journal of scientific studies related to fundamental themes in Life Sciences, especially those concerned with the origins of life and evolution of biosystems. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers.
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