[New 2023 ESC Guidelines for the management of endocarditis].

Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-11-01 Epub Date: 2024-10-22 DOI:10.1055/a-2263-3573
Frank Arnold Flachskampf
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Abstract

A succinct summary of the 2023 guidelines on the management of infectious endocarditis of the European Society of Cardiology is presented. Main new aspects are (1) the importance of treating complicated endocarditis at a hospital with an endocarditis team and cardiac surgery, (2) a less restrictive recommendation for antibiotic prophylaxis, which now favors an individualized indication in patients with intermediary risk, e.g. bicuspid aortic valve and degenerative or rheumatic native valve disease, undergoing orodental interventions, while there is a clear recommendation for prophylaxis in high-risk patients (e.g. having prosthetic valves). (3) In patients with left-sided endocarditis caused by streptococci, enterococcus faecalis, staphylococcus aureus, or coagulase-negative staphylococci, who are stable after at least 10 days of in-hospital intravenous appropriate antibiotic therapy, step-down ambulatory (oral or parenteral) further antibiotic therapy is recommended.

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[2023年ESC心内膜炎治疗新指南]。
本文简要介绍了欧洲心脏病学会 2023 年感染性心内膜炎治疗指南。主要新内容包括:(1)在拥有心内膜炎团队和心脏外科的医院治疗复杂性心内膜炎的重要性;(2)对抗生素预防的建议限制较少,现在倾向于对中危患者(如主动脉瓣双尖瓣、退行性或风湿性原发瓣膜病、接受口腔介入治疗的患者)进行个体化指征,同时明确建议对高危患者(如人工瓣膜)进行预防。(3) 对于由链球菌、粪肠球菌、金黄色葡萄球菌或凝固酶阴性葡萄球菌引起的左侧心内膜炎患者,如果经过至少 10 天的院内静脉适当抗生素治疗后病情稳定,则建议进行降级的非卧床(口服或肠道外)进一步抗生素治疗。
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