Impact of an Adult Congenital Heart Disease Order Set in a Pediatric Cardiac Intensive Care Unit.

Ashley Park, Brynn Connor, Pranava Sinha, Melissa Jones, Ricardo Munoz, Aminah Baxter, Seiji Ito, Anitha John
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Abstract

Background: Patients with congenital heart disease (CHD) are increasingly surviving to adulthood. Given their age- and condition-specific needs, the optimal postoperative setting for these patients is not yet determined. This study aims to evaluate the utility of an adult-specific order set in improving clinical outcomes for these patients in a pediatric cardiovascular intensive care unit (ICU). Methods: Adults with CHD (ACHD) admitted to the cardiovascular ICU following cardiac surgery at a pediatric tertiary care center were identified for a retrospective cohort study. Health care delivery metrics and clinical outcomes of participants who received the adult-specific order set were compared with control patients admitted prior to the intervention. Categorical outcomes were compared using the χ2 test of independence or Fisher exact test, and continuous outcomes were assessed using the t test. Results: A total of 130 ACHD patients received the intervention, with no significant differences observed in clinical outcomes when compared with 89 controls. While there was additionally no reduction in hospital-related mortality (2.3% vs 7.8%, RR 0.3; P = .1), clinician ordering behaviors were better aligned with best-practices following the intervention. Among patients with moderate or greater anatomic complexity, a post hoc analysis demonstrated reduced in-hospital mortality from those who received the adult order set. Conclusions: The implementation of an adult-specific order set in a pediatric care setting did not improve clinical outcomes for all ACHD patients. Patients with moderate and greater anatomic complexity did see a mortality benefit, suggestive that targeted electronic tools may most benefit those who have the highest risk.

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成人先天性心脏病医嘱集对儿科心脏重症监护病房的影响。
背景:先天性心脏病(CHD)患者越来越多地存活到成年。鉴于其年龄和病情的特殊需要,这些患者的最佳术后环境尚未确定。本研究旨在评估成人专用医嘱集在改善儿科心血管重症监护病房(ICU)中此类患者临床疗效方面的效用。方法:在一项回顾性队列研究中,确定了在一家儿科三级医疗中心接受心脏手术后入住心血管重症监护病房的成人先天性心脏病患者(ACHD)。将接受成人专用医嘱集的参与者与干预前的对照组患者的医疗服务指标和临床结果进行了比较。分类结果采用χ2独立性检验或费雪精确检验进行比较,连续结果采用t检验进行评估。结果共有 130 名 ACHD 患者接受了干预,与 89 名对照组相比,临床结果无明显差异。虽然医院相关死亡率没有降低(2.3% vs 7.8%,RR 0.3;P = .1),但干预后临床医生的排序行为更符合最佳实践。在具有中等或更高解剖复杂性的患者中,一项事后分析显示,接受成人医嘱集的患者的院内死亡率有所降低。结论在儿科护理环境中实施成人专用医嘱并不能改善所有 ACHD 患者的临床治疗效果。中度和高度解剖复杂性患者的死亡率确实有所改善,这表明有针对性的电子工具可能会使风险最高的患者受益。
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