Jiahui Su, Meirong Huang, Zichun Yan, Shengbiao Tang, Xinhao Zhang, Jiangtao Sun
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引用次数: 0
Abstract
We report here the use of pyridin-2-yl benzenesulfonates as sulfonylation reagents in a difunctionalization reaction based on oxy-pyridinium ylide chemistry, providing an effective protocol for the installation of both a sulfonyl group and a pyridone moiety into one molecule. Density functional theory (DFT) calculations disclose that the reaction process might proceed through sequential metal-bound ylide formation, keto-enol tautomerism, and the migratory rearrangement of the sulfonyl group.
期刊介绍：
Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.
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