Stimulation of the withdrawal reflex in gait training after stroke: A systematic review and meta-analysis.

IF 2.2 3区 医学 Q3 ENGINEERING, BIOMEDICAL Artificial organs Pub Date : 2024-10-28 DOI:10.1111/aor.14894
Carmen Krewer, Elaine Fischer, Erika G Spaich, Klaus Jahn
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Abstract

Background: After a stroke many people experience hemiparesis, resulting in walking difficulties which affects independence, mobility, and participation in activities of daily living. Activating the nociceptive withdrawal reflex (NWR) during gait training aims to support the initiation and facilitation of the swing phase of the paretic leg. The aim of this review is to investigate the orthotic and therapeutic effects of a NWR stimulation intervention to improve gait in patients after a stroke.

Methods: We searched the databases CENTRAL, DORIS, MEDLINE, and PEDro, trial registers and reference lists. We selected randomized controlled trials using any type of stimulation of the NWR in people after stroke, comparing it to any control intervention, and reporting a change in gait performance assessed by means of any appropriate measurement method.

Results: We included three studies in this review, all of which used electrical stimulation to elicit the NWR during walking. The orthotic effect was investigated in one study, and the therapeutic effect in two studies, comparing walking with and without electrical stimulation-triggered NWR. The meta-analysis revealed a borderline statistical significance result for the therapeutic effect. The pooled mean difference between the treatment and control group (random-effects model) for walking speed was 0.13 m/s (95% CI -0.04 to 0.29; I2 = 72%) after treatment and 0.17 m/s (95% CI -0.03 to 0.37; I2 = 62%) at follow-up.

Conclusion: Activating the NWR during gait training has not been investigated frequently so far. By using electrical stimulation-elicited NWR, severely affected hemiparetic patients may improve their walking speed.

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中风后步态训练中的退缩反射刺激:系统回顾与荟萃分析。
背景:许多人在中风后会出现偏瘫,导致行走困难,影响独立性、活动能力和日常生活活动的参与。在步态训练中激活痛觉退缩反射(NWR)的目的是支持瘫痪腿摆动阶段的启动和促进。本综述旨在研究 NWR 刺激干预对改善中风后患者步态的矫形和治疗效果:我们检索了 CENTRAL、DORIS、MEDLINE 和 PEDro 等数据库、试验登记簿和参考文献列表。我们选择了对中风后的患者使用任何类型的刺激 NWR 的随机对照试验,将其与任何对照干预进行比较,并通过任何适当的测量方法评估步态表现的变化:本综述共纳入三项研究,所有研究均使用电刺激在步行过程中激发 NWR。其中一项研究对矫形效果进行了调查,两项研究对治疗效果进行了调查,并比较了有无电刺激触发 NWR 的步行效果。荟萃分析表明,治疗效果的统计显著性处于边缘水平。治疗后,治疗组与对照组步行速度的汇总平均差异(随机效应模型)为 0.13 米/秒(95% CI -0.04 至 0.29;I2 = 72%),随访时为 0.17 米/秒(95% CI -0.03 至 0.37;I2 = 62%):结论:迄今为止,在步态训练过程中激活NWR的研究并不多见。结论:在步态训练中激活NWR的研究迄今为止并不多见。通过使用电刺激引发的NWR,严重偏瘫患者可以提高步行速度。
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来源期刊
Artificial organs
Artificial organs 工程技术-工程:生物医学
CiteScore
4.30
自引率
12.50%
发文量
303
审稿时长
4-8 weeks
期刊介绍: Artificial Organs is the official peer reviewed journal of The International Federation for Artificial Organs (Members of the Federation are: The American Society for Artificial Internal Organs, The European Society for Artificial Organs, and The Japanese Society for Artificial Organs), The International Faculty for Artificial Organs, the International Society for Rotary Blood Pumps, The International Society for Pediatric Mechanical Cardiopulmonary Support, and the Vienna International Workshop on Functional Electrical Stimulation. Artificial Organs publishes original research articles dealing with developments in artificial organs applications and treatment modalities and their clinical applications worldwide. Membership in the Societies listed above is not a prerequisite for publication. Articles are published without charge to the author except for color figures and excess page charges as noted.
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