Injecting drug use is a risk factor for methicillin resistance in patients with Staphylococcus aureus bloodstream infections

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Internal Medicine Journal Pub Date : 2024-10-29 DOI:10.1111/imj.16529
Stephanie J. Curtis, Timothy Marvelianto Tedjo, Sue J. Lee, Philip J. Rawson-Harris, Kirsty Sim, Lucy O. Attwood, Adam W. J. Jenney, Andrew J. Stewardson
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Abstract

We investigated whether injecting drug use was a risk factor for methicillin resistance among inpatients with Staphylococcus aureus bloodstream infections (SABSIs) at an Australian health service. In 273 inpatients, 46 (16.9%) of SABSIs were methicillin-resistant S. aureus (MRSA). MRSA was more frequent in those who had injected drugs in the past 6 months (20.6%) compared with other inpatients (15.7%). Injecting drug use was associated with a 4.82-fold (95% confidence interval = 1.54–16.29) increased odds of MRSA after accounting for confounders.

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注射吸毒是金黄色葡萄球菌血流感染患者耐甲氧西林的一个风险因素。
我们调查了注射吸毒是否是澳大利亚一家医疗服务机构的金黄色葡萄球菌血流感染(SABSI)住院患者耐甲氧西林的一个风险因素。在 273 名住院患者中,46 例(16.9%)SABSI 为耐甲氧西林金黄色葡萄球菌(MRSA)。与其他住院病人(15.7%)相比,在过去 6 个月中注射过毒品的病人(20.6%)更容易感染 MRSA。在考虑了混杂因素后,注射毒品与 MRSA 发生几率增加 4.82 倍(95% 置信区间 = 1.54-16.29)有关。
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来源期刊
Internal Medicine Journal
Internal Medicine Journal 医学-医学:内科
CiteScore
3.50
自引率
4.80%
发文量
600
审稿时长
3-6 weeks
期刊介绍: The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.
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