Edinburgh postnatal depression scale score elevation in caregivers of infants with cystic fibrosis.

IF 2.7 3区医学 Q1 PEDIATRICS Pediatric Pulmonology Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI:10.1002/ppul.27364

Michelle L Gillespie, Swati Jayaram, Mariah Eisner, Stephanie Sliemers, Kimberly Pasley, Karen McCoy, Katelyn Krivchenia

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Abstract

Introduction: The diagnosis of cystic fibrosis (CF) can impact the mental health of caregivers. This study aimed to explore prevalence of postpartum depression (PPD) symptoms in caregivers of infants with CF or CFTR-related metabolic syndrome (CRMS).

Methods: This prospective, observational study was conducted in a CF clinic at a tertiary hospital over 4 years. Caregivers of infants with CF/CRMS completed serial surveys over the first year of life. Surveys included the Edinburgh Postnatal Depression Scale (EPDS), Patient Health Questionnaire-9 (PHQ-9) and the General Anxiety Disorder-7 (GAD-7). A control group of healthy infant caregivers was used for comparative analysis of EPDS scores.

Results: Analyses were conducted on 55 caregivers of 42 infants with CF/CRMS and 915 caregivers of healthy infants. Caregivers of infants with CF/CRMS had a significantly higher prevalence of elevated EPDS scores and higher mean EPDS scores for visit 1 (age 1-2mo) and visit 3 (age 6-9mo) compared to healthy controls (p < 0.001 for both). There was a higher prevalence of caregivers identifying thoughts of self-harm in the CF/CRMS cohort (8.3%) compared to caregivers of healthy controls (1.2%) at visit 1 (p = 0.015) and at visit 3 (CF/CRMS 8.8%; control 1.7%; p = 0.030). EPDS scores correlated with PHQ-9 and GAD-7 scores, particularly earlier in the infant's life.

Conclusions: Caregivers of infants with CF/CRMS may be at higher risk of PPD and thoughts of self-harm when compared to healthy controls. Given what is known about the impact of PPD on mental and physical health of children, early identification is vital for this population.

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爱丁堡产后抑郁量表对囊性纤维化婴儿护理者的评分升高。

导言：囊性纤维化（CF）的诊断会影响照顾者的心理健康。本研究旨在探讨CF或CFTR相关代谢综合征（CRMS）婴儿护理者产后抑郁症（PPD）症状的发生率：这项前瞻性观察研究在一家三甲医院的 CF 诊所进行，历时 4 年。CF/CRMS患儿的照顾者在患儿出生后的第一年内完成了一系列调查。调查内容包括爱丁堡产后抑郁量表（EPDS）、患者健康问卷-9（PHQ-9）和一般焦虑症-7（GAD-7）。在对 EPDS 评分进行比较分析时，还使用了由健康婴儿护理人员组成的对照组：对 42 名 CF/CRMS 婴儿的 55 名照护者和 915 名健康婴儿的照护者进行了分析。与健康对照组相比，CF/CRMS 婴儿的看护者 EPDS 分数升高的发生率明显更高，第 1 次就诊（1-2 个月）和第 3 次就诊（6-9 个月）的平均 EPDS 分数也更高（P 结论：与健康对照组相比，CF/CRMS 婴儿的看护者 EPDS 分数升高的发生率明显更高：与健康对照组相比，患有 CF/CRMS 的婴儿的照顾者患 PPD 和自残念头的风险可能更高。鉴于目前已知的 PPD 对儿童身心健康的影响，早期识别对这一人群至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Pulmonology 医学-呼吸系统

CiteScore

6.00

自引率

12.90%

发文量

468

审稿时长

3-8 weeks

期刊介绍： Pediatric Pulmonology (PPUL) is the foremost global journal studying the respiratory system in disease and in health as it develops from intrauterine life though adolescence to adulthood. Combining explicit and informative analysis of clinical as well as basic scientific research, PPUL provides a look at the many facets of respiratory system disorders in infants and children, ranging from pathological anatomy, developmental issues, and pathophysiology to infectious disease, asthma, cystic fibrosis, and airborne toxins. Focused attention is given to the reporting of diagnostic and therapeutic methods for neonates, preschool children, and adolescents, the enduring effects of childhood respiratory diseases, and newly described infectious diseases. PPUL concentrates on subject matters of crucial interest to specialists preparing for the Pediatric Subspecialty Examinations in the United States and other countries. With its attentive coverage and extensive clinical data, this journal is a principle source for pediatricians in practice and in training and a must have for all pediatric pulmonologists.