Squamous Cell Carcinoma with Prominent Eosinophils.

IF 3.2 Q2 PATHOLOGY Head & Neck Pathology Pub Date : 2024-10-28 DOI:10.1007/s12105-024-01718-2
Thomas N Helm, Sanica Bhele, Julie C Fanburg-Smith
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Abstract

Eosinophils are often encountered in the stroma and peritumoral microenvironment of squamous cell carcinomas. Because eosinophils are readily identified on routine hematoxylin and eosin stained sections, researchers have explored multiple ways in which identifying the extent of eosinophil infiltration on routine biopsy and excisional specimens might provide diagnostic and prognostic information. We review the literature on this evolving topic.

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鳞状细胞癌伴有明显的嗜酸性粒细胞。
鳞状细胞癌的基质和瘤周微环境中经常会出现嗜酸性粒细胞。由于嗜酸性粒细胞很容易在常规苏木精和伊红染色的切片上被识别出来,研究人员探索了多种方法,以确定嗜酸性粒细胞在常规活检和切除标本上的浸润程度,从而提供诊断和预后信息。我们对这一不断发展的课题进行了文献综述。
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来源期刊
CiteScore
5.70
自引率
9.50%
发文量
99
期刊介绍: Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.
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