Light-induced isomerization of quinoline-N-oxide derivatives through Zn-catalysis: a photochemical approach for synthesizing 2-quinolinone derivatives†
Xiaoqiang Yu, Sana Yang, Ning Yan, Yukang Fu, Yang Li, Wanhui Wang and Ming Bao
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引用次数: 0
Abstract
A novel strategy for the synthesis of quinolin-2(1H)-one and its related derivatives is described. The light-induced Zn-catalyzed isomerization of quinoline-N-oxides proceeds smoothly to afford 2-quinolinones in satisfactory to high yields. Control experiments and computational studies demonstrate that this photochemical isomerization reaction proceeds through an intramolecular hydrogen and oxygen transfer reaction, ensuring 100% atomic economy.
期刊介绍：
Green Chemistry is a journal that provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998), which defines green chemistry as the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry aims to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The journal welcomes submissions on all aspects of research relating to this endeavor and publishes original and significant cutting-edge research that is likely to be of wide general appeal. For a work to be published, it must present a significant advance in green chemistry, including a comparison with existing methods and a demonstration of advantages over those methods.
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