Mr Muhammad Nazmi Zulkafli , Mrs Ann Erynna Lema Thomas Sudin , DR Noor Shafini Mohamad , DR Nazimah Ab Mumin , DR Roqiah Fatmawati Abdul Kadir , Miss Siti Hawa Mahfar
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引用次数: 0
Abstract
Background / Purpose
This study aimed to investigate the effectiveness of the test-bolus technique application for Computed Tomography Pulmonary Angiography (CTPA) in COVID-19 patients by analyzing contrast media volume and radiation dose reduction, and image quality.
Methods
This is a retrospective study of 32 CTPA images from Hospital Al-Sultan Abdullah (HASA) (Group A) and University Malaya Medical Centre (Group B) with clinical suspicion for PE from 1st February 2021 to 1st May 2021. Group A (N=16) received test-bolus technique (35ml of 370mg/I at 5ml/s) and Group B (N=16) received bolus-tracking technique (50ml of 370mg/I at 5ml/s) and were scanned by 128-slice Siemens Somatom Definition AS (Siemens Healthcare, Forchheim, Germany) CT scan machine. For analysis, subjective image quality was done by two board-certified radiologists independently (both 7 years’ experience) using a 5-point Likert's scale at an axial image at the level of the pulmonary artery. Objective image quality analysis was done by measuring contrast enhancement at the MPA, RPA, LPA, left upper and lower lobe PA, apical segment artery and vein, basal segment artery and vein. The CTDIvol, dose-length product (DLP) and Effective dose (E) were measured. The volume of contrast media was recorded.
Results
Group A mean contrast volume was (38.13ml ± 2.5ml) compared to Group B (56.25ml ± 8.85ml), (P<0.005), leading to a 32.21% contrast reduction (p=0.000). 8.8% of dose increase in mean CTDIvol in group A (16.45mGy±3.43mGy) compared to group B (15mGy ± 2.8mGy) (p=0.200). For mean DLP and effective dose, the dose increase was 9.2% in group A (204.38mGycm ± 47.42mGycm), (3.27mSv ± 0.76 mSv) compared to group B (185.56mGycm ± 16.97mGycm), (2.97mSv ± 0.27mSv), with p=0.152 each.
Conclusion(s)
This study proved that the test-bolus technique application is effective in reducing contrast media volume usage for CTPA in COVID-19 patients with suspected PE.
期刊介绍：
Journal of Medical Imaging and Radiation Sciences is the official peer-reviewed journal of the Canadian Association of Medical Radiation Technologists. This journal is published four times a year and is circulated to approximately 11,000 medical radiation technologists, libraries and radiology departments throughout Canada, the United States and overseas. The Journal publishes articles on recent research, new technology and techniques, professional practices, technologists viewpoints as well as relevant book reviews.
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