Effectiveness of paediatric asthma hubs: a clinical pilot study.

IF 4.3 3区 医学 Q1 PEDIATRICS Archives of Disease in Childhood Pub Date : 2024-10-29 DOI:10.1136/archdischild-2023-326635
Ali Hakizimana, David K H Lo, Damian Roland, Vinayak K Rai, Lesley Danvers, Rachel Rowlands, Molla Imaduddin Ahmed, Reeta Herzallah, Erol A Gaillard
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Abstract

Background: Children and young people (CYP) with asthma in the UK are at higher risk of poor outcomes compared with other high-income European countries due to factors including poor access to high-quality asthma reviews, diagnostic testing and inconsistent postattack reviews. The Leicester Integrated Care Board funded the first UK pilot asthma hub for CYP, to investigate the feasibility and effectiveness of hubs, in providing postattack reviews along with providing asthma education, the opportunity to carry out diagnostic lung function tests and optimise treatment.

Methods: Clinical pilot study including CYP aged 4-17 years referred to the hub with uncontrolled asthma or postattack from November 2021 to April 2022. CYP received a structured clinical assessment including National Institute for Health and Care Excellence (NICE) first-line diagnostic investigations for asthma including spirometry, bronchodilator reversibility (BDR) and fraction of exhaled nitric oxide (FeNO).

Results: Of 312 CYP referred (mean age 8.6±3.2 years; 42% women), 266 (85.3%) attended their appointment. Median time from referral to review was 2 days (IQR 1-3). Three CYP (1.1%) were severely unwell at review and required further hospital treatment. In the 231 CYP who completed first-line tests, asthma was confirmed for 73 (31.6%) based on NICE diagnostic criteria for CYP. Twenty-two per cent of children with normal baseline spirometry had ≥12% BDR.

Conclusion: Paediatric asthma hubs are a feasible model of care to deliver CYP postasthma attack reviews and identify high-risk patients requiring further treatment. Spirometry, BDR and FeNO testing allowed diagnostic confirmation in a significant proportion of CYP.

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儿科哮喘中心的有效性:一项临床试验研究。
背景:与其他高收入欧洲国家相比,英国患有哮喘的儿童和青少年(CYP)的治疗效果不佳的风险较高,原因包括难以获得高质量的哮喘复查、诊断检测和不一致的发作后复查。莱斯特综合护理委员会资助了英国首个针对青少 年的哮喘中心试点项目,目的是研究中心在提供哮喘教育、诊断性肺功能测试和优化治疗的同时,提供哮喘发作后复查的可行性和有效性:临床试验研究包括 2021 年 11 月至 2022 年 4 月期间因哮喘未得到控制或哮喘发作后转诊至中心的 4-17 岁青少 年。青少 年接受结构化临床评估,包括国家健康与护理优化研究所(NICE)哮喘一线诊断检查,包括肺活量、支气管扩张剂可逆性(BDR)和呼出一氧化氮分数(FeNO):在转诊的 312 名 CYP 患者(平均年龄为 8.6±3.2 岁;42% 为女性)中,有 266 人(85.3%)赴约就诊。从转诊到复查的中位时间为 2 天(IQR 1-3)。有 3 名儿童青少年(1.1%)在复查时身体严重不适,需要进一步住院治疗。在完成一线检测的 231 名儿童青少年中,有 73 人(31.6%)根据 NICE 儿童青少年诊断标准确诊为哮喘。基线肺活量正常的儿童中有 22% 的 BDR ≥12%:儿童哮喘中心是一种可行的护理模式,可提供哮喘发作后复查,并识别需要进一步治疗的高风险患者。肺活量、BDR 和 FeNO 测试可对相当一部分 CYP 进行诊断确认。
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来源期刊
CiteScore
5.80
自引率
3.80%
发文量
291
审稿时长
3-6 weeks
期刊介绍: Archives of Disease in Childhood is an international peer review journal that aims to keep paediatricians and others up to date with advances in the diagnosis and treatment of childhood diseases as well as advocacy issues such as child protection. It focuses on all aspects of child health and disease from the perinatal period (in the Fetal and Neonatal edition) through to adolescence. ADC includes original research reports, commentaries, reviews of clinical and policy issues, and evidence reports. Areas covered include: community child health, public health, epidemiology, acute paediatrics, advocacy, and ethics.
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