Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study.

IF 2.8 3区医学 Q3 ENDOCRINOLOGY & METABOLISM BMC Endocrine Disorders Pub Date : 2024-10-29 DOI:10.1186/s12902-024-01721-2

Jinbang Wang, Yunting Zhou, Yu Liu, Miaomiao Sang, Yuzhi Ding, Tingting Li, Xiaohang Wang, Vladmir Carvalho, Chengming Ni, Qianqian Wang, Zhensheng Cai, Huan Wang, Yang Chen, Zhanjia Shang, Duolao Wang, Shanhu Qiu, Zilin Sun

{"title":"Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study.","authors":"Jinbang Wang, Yunting Zhou, Yu Liu, Miaomiao Sang, Yuzhi Ding, Tingting Li, Xiaohang Wang, Vladmir Carvalho, Chengming Ni, Qianqian Wang, Zhensheng Cai, Huan Wang, Yang Chen, Zhanjia Shang, Duolao Wang, Shanhu Qiu, Zilin Sun","doi":"10.1186/s12902-024-01721-2","DOIUrl":null,"url":null,"abstract":"Aims: Night blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.Methods: This multi-center, cross-sectional study enrolled a total of 5664 participants aged 18-82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.Results: A total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.Conclusions: The results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.","PeriodicalId":9152,"journal":{"name":"BMC Endocrine Disorders","volume":"24 1","pages":"231"},"PeriodicalIF":2.8000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11520579/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Endocrine Disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12902-024-01721-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: Night blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults.

Methods: This multi-center, cross-sectional study enrolled a total of 5664 participants aged 18-82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes.

Results: A total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes.

Conclusions: The results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

中国人群夜盲史与糖尿病风险之间的关系：一项多中心横断面研究。

目的：夜盲症（NB）是视网膜缺损的一种重要表现，可能与糖尿病的发病几率有关。本研究旨在探讨中国社区成人夜盲症病史与糖尿病之间的可能关联：这项多中心横断面研究从中国的八个地点共招募了 5664 名年龄在 18-82 岁之间的参与者。通过标准化问卷收集了人口统计学和病史信息。糖尿病的诊断依据是口服葡萄糖耐量试验或自述病史。NB病史是参照世界卫生组织的建议，通过面对面访谈确定的。采用逻辑回归分析评估 NB 病史与糖尿病几率之间的关联：最终共纳入 5049 名参与者，其中 252 人有 NB 史，1076 人患有糖尿病。研究对象的平均年龄为 52.9 岁，有 NB 病史者的比例明显高于无 NB 病史者（7.0% 对 4.5%）。与无 NB 史的参与者相比，有 NB 史的参与者患糖尿病的多变量调整几率比为 1.41（95% 置信区间为 1.06，1.89）。此外，中介分析表明，以腰围-身高比评估的肥胖在一定程度上中介了NB史与糖尿病几率增加之间的关系：结论：研究结果表明，在中国社区居住的成年人中，NB史可能与糖尿病患病几率增加有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-

CiteScore

4.40

自引率

0.00%

发文量

280

审稿时长

>12 weeks

期刊介绍： BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.