Calciphylaxis Mimicking Giant Cell Arteritis: A Case Report.

IF 0.5 Q4 OPHTHALMOLOGY Case Reports in Ophthalmology Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI:10.1159/000541410

Nada Alyousef, Wael A Alsakran, Azza Maktabi

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Abstract

Introduction: Calciphylaxis is a condition that causes vascular calcification and intimal proliferation with thrombotic occlusion of small-to-medium-sized vessels.

Case presentation: We describe a case of a 64-year-old woman who presented with a clinical picture that was suggestive of anterior arteritic ischemic optic neuropathy due to giant cell arteritis (GCA), but was found to have calciphylaxis confirmed by histologic examination. When calciphylaxis affects the blood supply to the eye, commonly it causes sudden vision loss, pallid optic disk edema, and a relative afferent pupillary defect, all of which were observed in our patient.

Conclusion: There is no known cure for calciphylaxis, while in GCA, high-dose corticosteroid therapy is essential to prevent involvement of the contralateral eye. As the management approaches for these two diseases are different, it is important to have performed a thorough clinical examination along with detailed histopathological testing to rule out calciphylaxis of the temporal artery in patients suspected to have GCA.

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模仿巨细胞动脉炎的钙化病：病例报告

导言：钙化症是一种导致血管钙化和内膜增生并伴有中小型血管血栓性闭塞的疾病：我们描述了一例 64 岁女性的病例，她的临床表现提示为巨细胞动脉炎（GCA）引起的前动脉缺血性视神经病变，但经组织学检查发现她患有钙化症。当钙化病影响到眼睛的血液供应时，通常会导致视力突然下降、视盘苍白水肿和瞳孔相对传入缺损，我们的患者就出现了这些症状：结论：目前尚无治疗钙睫症的方法，而对于 GCA，大剂量皮质类固醇治疗对防止对侧眼受累至关重要。由于这两种疾病的治疗方法不同，因此对怀疑患有 GCA 的患者进行全面的临床检查和详细的组织病理学检测以排除颞动脉钙化症是非常重要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Ophthalmology OPHTHALMOLOGY-

CiteScore

0.90

自引率

0.00%

发文量

129

审稿时长

12 weeks

期刊介绍： This peer-reviewed online-only journal publishes original case reports covering the entire spectrum of ophthalmology, including prevention, diagnosis, treatment, toxicities of therapy, supportive care, quality-of-life, and survivorship issues. The submission of negative results is strongly encouraged. The journal will also accept case reports dealing with the use of novel technologies, both in the arena of diagnosis and treatment. Supplementary material is welcomed. The intent of the journal is to provide clinicians and researchers with a tool to disseminate their personal experiences to a wider public as well as to review interesting cases encountered by colleagues all over the world. Universally used terms can be searched across the entire growing collection of case reports, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.