Transforming Lung Cancer Care: The Role of Transferosomes in Modern Drug Delivery.

IF 3.5 4区 医学 Q3 ONCOLOGY Current cancer drug targets Pub Date : 2025-01-01 DOI:10.2174/0115680096329205240905053934
Basavaraju Suresh, Nimbagal Raghavendra Naveen, Prakash S Goudanavar
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Abstract

Cancer stands as one of the leading causes of death worldwide, and lung cancer represents its most aggressive and persistent form. Traditional strategies for addressing lung cancer involve various medical therapies such as radiotherapy, chemotherapy, and surgical excision. Despite their prevalence, these conventional methods lack precision and inadvertently cause collateral damage to neighbouring healthy cells. Recently, nanotechnology has emerged as a potential strategy for the treatment and management of lung carcinomas, bringing about a transformative shift in existing approaches. The primary focus of this shift is on minimizing harmful effects and improving the bioavailability of chemotherapy drugs specifically targeted at tumour cells. Currently, transferosome nanocarrier systems are widely employed to overcome the obstacles presented by lung cancer. The utilisation of transferosomeloaded therapeutic medication administration technologies holds tremendous potential in regulating tumour cell growth and treating lung cancer. The purpose of this study is to provide an overview and analysis of current advancements in transferosome-based drug delivery systems, employing inhalational nanoparticle strategies for precise drug targeting in lung cancer management.

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肺癌治疗的变革:转移体在现代给药中的作用。
癌症是导致全球死亡的主要原因之一,而肺癌是最具侵袭性和顽固性的癌症。传统的肺癌治疗策略包括各种医学疗法,如放疗、化疗和手术切除。尽管这些传统方法很普遍,但它们缺乏精确性,而且会无意中对邻近的健康细胞造成附带损害。最近,纳米技术已成为治疗和管理肺癌的一种潜在策略,为现有方法带来了变革性的转变。这种转变的主要重点是最大限度地减少化疗药物对肿瘤细胞的有害影响,并提高化疗药物的生物利用度。目前,转移体纳米载体系统被广泛应用于克服肺癌带来的障碍。利用转运体载药技术在调节肿瘤细胞生长和治疗肺癌方面具有巨大潜力。本研究的目的是概述和分析基于转运体的给药系统的当前进展,采用吸入式纳米粒子策略在肺癌治疗中实现精确的药物靶向。
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来源期刊
Current cancer drug targets
Current cancer drug targets 医学-肿瘤学
CiteScore
5.40
自引率
0.00%
发文量
105
审稿时长
1 months
期刊介绍: Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes. Current Cancer Drug Targets publishes original research articles, letters, reviews / mini-reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cancer. As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.
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