Neighborhood homicide rate and odds of colorectal adenoma among adult patients seeking colonoscopy.

IF 3.4 Q2 ONCOLOGY JNCI Cancer Spectrum Pub Date : 2024-10-29 DOI:10.1093/jncics/pkae110
Alyshia Hamm, Evgenia Karayeva, Manoela Lima Oliveira, Nabil Kahouadji, Paul Grippo, Patricia G Wolf, Ece Mutlu, Lisa Tussing-Humphreys, Sage J Kim
{"title":"Neighborhood homicide rate and odds of colorectal adenoma among adult patients seeking colonoscopy.","authors":"Alyshia Hamm, Evgenia Karayeva, Manoela Lima Oliveira, Nabil Kahouadji, Paul Grippo, Patricia G Wolf, Ece Mutlu, Lisa Tussing-Humphreys, Sage J Kim","doi":"10.1093/jncics/pkae110","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Chronic exposure to ambient stressors, including neighborhood crime, may have a detrimental impact on the body's stress response system with implications for colorectal carcinogenesis.</p><p><strong>Methods: </strong>We examined associations between the mean neighborhood homicide rates from 2000 and 2018 and diagnosis of colorectal adenoma among patients at the University of Illinois Health and Hospital System in Chicago, Illinois, between 2015 and 2018.</p><p><strong>Results: </strong>Of the 5,225 patients who underwent colonoscopy and were included in the analytic dataset, 60% had colorectal adenoma. Older age, male sex, and higher body mass index (BMI) were associated with greater odds of colorectal adenoma. The neighborhood homicide rate was associated with identifying as Black and Hispanic and higher BMI. A mediation analysis showed that the neighborhood homicide rate effects on colorectal adenoma were mediated through BMI.</p><p><strong>Conclusion: </strong>The study concluded that older age, male sex, and higher BMI significantly increase the odds of colorectal adenoma, with neighborhood homicide rate indirectly influencing this risk through its association with BMI, particularly among Black and Hispanic individuals.</p>","PeriodicalId":14681,"journal":{"name":"JNCI Cancer Spectrum","volume":null,"pages":null},"PeriodicalIF":3.4000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JNCI Cancer Spectrum","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/jncics/pkae110","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Chronic exposure to ambient stressors, including neighborhood crime, may have a detrimental impact on the body's stress response system with implications for colorectal carcinogenesis.

Methods: We examined associations between the mean neighborhood homicide rates from 2000 and 2018 and diagnosis of colorectal adenoma among patients at the University of Illinois Health and Hospital System in Chicago, Illinois, between 2015 and 2018.

Results: Of the 5,225 patients who underwent colonoscopy and were included in the analytic dataset, 60% had colorectal adenoma. Older age, male sex, and higher body mass index (BMI) were associated with greater odds of colorectal adenoma. The neighborhood homicide rate was associated with identifying as Black and Hispanic and higher BMI. A mediation analysis showed that the neighborhood homicide rate effects on colorectal adenoma were mediated through BMI.

Conclusion: The study concluded that older age, male sex, and higher BMI significantly increase the odds of colorectal adenoma, with neighborhood homicide rate indirectly influencing this risk through its association with BMI, particularly among Black and Hispanic individuals.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
邻里凶杀率与寻求结肠镜检查的成年患者患结直肠腺瘤的几率。
背景:长期暴露于环境应激源(包括社区犯罪)可能会对人体的应激反应系统产生不利影响,并对大肠癌的发生产生影响:长期暴露于包括邻里犯罪在内的环境应激源可能会对人体的应激反应系统产生不利影响,从而对结直肠癌的发生产生影响:我们研究了伊利诺伊州芝加哥市伊利诺伊大学健康与医院系统的患者在2015年至2018年期间,2000年至2018年社区凶杀案平均发生率与结直肠腺瘤诊断之间的关联:在接受结肠镜检查并纳入分析数据集的5225名患者中,60%患有结直肠腺瘤。年龄越大、性别为男性、体重指数(BMI)越高,患结直肠腺瘤的几率越大。邻里凶杀率与黑人和西班牙裔以及较高的体重指数有关。中介分析表明,邻里凶杀率对结直肠腺瘤的影响是通过体重指数中介的:研究结论:年龄较大、男性和较高的体重指数会显著增加患结直肠腺瘤的几率,而邻里凶杀率则会通过与体重指数的关联间接影响这一风险,尤其是在黑人和西班牙裔人群中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
JNCI Cancer Spectrum
JNCI Cancer Spectrum Medicine-Oncology
CiteScore
7.70
自引率
0.00%
发文量
80
审稿时长
18 weeks
期刊最新文献
Association between GLP-1RA use and progression of MGUS to Multiple Myeloma among diabetic patients. Sexual Function and Satisfaction in Young Women with Breast Cancer: A Five-Year Prospective Study. County-level racial disparities in prostate cancer specific mortality from 2005 to 2020. Low CD86 expression is a predictive biomarker for clinical response to the therapeutic human papillomavirus vaccine IGMKK16E7: results of a post hoc analysis. Neighborhood vulnerability and associations with poor health-related quality of life among adult survivors of childhood cancer.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1