Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl-2 Family Proteins”

IF 3.7 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY IUBMB Life Pub Date : 2024-10-29 DOI:10.1002/iub.2921
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Abstract

Dasgupta A, Dey D, Ghosh D, Lai TK, Bhuvanesh N, Dolui S, Velayutham R, Acharya K. Astrakurkurone, a Sesquiterpenoid from wild edible mushroom, targets liver cancer cells by modulating Bcl-2 family proteins. IUBMB Life. 2019;71(7): 992–1002. https://doi.org/10.1002/iub.2047

An investigation based on concerns raised by a third party revealed the duplication of figure panels between Figure 3A and C, and high similarity between Figure 5B I Caspase 9 and GAPDH lanes, and 5B II Bax and Caspase 2 lanes. The authors admitted to the image compilation error in Figure 3 and were able to provide the original images of the article. The original images provided could not fully address the raised concerns, therefore the authors have repeated these experiments. The new experiments confirmed their earlier results, thus the corresponding conclusions of the paper remain unaffected. The new, corrected Figures 3 and 5 are shown as follows.

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对 "野生食用菌中的一种倍半萜类化合物 Astrakurkurone 通过调节 Bcl-2 家族蛋白靶向肝癌细胞 "的更正。
Dasgupta A, Dey D, Ghosh D, Lai TK, Bhuvanesh N, Dolui S, Velayutham R, Acharya K. Astrakurkurone,一种来自野生食用菌的倍半萜化合物,通过调节 Bcl-2 家族蛋白靶向肝癌细胞。IUBMB Life.2019;71(7):https://doi.org/10.1002/iub.2047An,根据第三方提出的疑虑进行调查,发现图3A和C之间的图板重复,图5B I Caspase 9和GAPDH泳道以及图5B II Bax和Caspase 2泳道之间高度相似。作者承认图 3 的图像编译有误,并能提供文章的原始图像。所提供的原始图片无法完全解决所提出的问题,因此作者重复了这些实验。新的实验证实了他们之前的结果,因此文章的相应结论不受影响。修正后的新图 3 和图 5 如下所示。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
IUBMB Life
IUBMB Life 生物-生化与分子生物学
CiteScore
10.60
自引率
0.00%
发文量
109
审稿时长
4-8 weeks
期刊介绍: IUBMB Life is the flagship journal of the International Union of Biochemistry and Molecular Biology and is devoted to the rapid publication of the most novel and significant original research articles, reviews, and hypotheses in the broadly defined fields of biochemistry, molecular biology, cell biology, and molecular medicine.
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