Defining the transcriptional lineages of breast cancer subtypes

IF 23.5 1区 医学 Q1 ONCOLOGY Nature cancer Pub Date : 2024-10-30 DOI:10.1038/s43018-024-00774-5
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Abstract

In this work, we demonstrate the transcriptional networks that link breast cancer subtypes and their cells of origin, and how transcriptional signatures differ between benign cells and cancer.

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确定乳腺癌亚型的转录谱系。
在这项工作中,我们展示了连接乳腺癌亚型及其起源细胞的转录网络,以及良性细胞和癌症之间的转录特征有何不同。
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来源期刊
Nature cancer
Nature cancer Medicine-Oncology
CiteScore
31.10
自引率
1.80%
发文量
129
期刊介绍: Cancer is a devastating disease responsible for millions of deaths worldwide. However, many of these deaths could be prevented with improved prevention and treatment strategies. To achieve this, it is crucial to focus on accurate diagnosis, effective treatment methods, and understanding the socioeconomic factors that influence cancer rates. Nature Cancer aims to serve as a unique platform for sharing the latest advancements in cancer research across various scientific fields, encompassing life sciences, physical sciences, applied sciences, and social sciences. The journal is particularly interested in fundamental research that enhances our understanding of tumor development and progression, as well as research that translates this knowledge into clinical applications through innovative diagnostic and therapeutic approaches. Additionally, Nature Cancer welcomes clinical studies that inform cancer diagnosis, treatment, and prevention, along with contributions exploring the societal impact of cancer on a global scale. In addition to publishing original research, Nature Cancer will feature Comments, Reviews, News & Views, Features, and Correspondence that hold significant value for the diverse field of cancer research.
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