Oral manifestations during dengue infection: a systematic review.

Gustavo Canales Sermeño, Marisel R Valenzuela Ramos, Pedro M Dias Monteiro, Dario E Medina Castro, Nicole K Medina Valera
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Abstract

Dengue is a global public health problem, especially in countries with tropical and subtropical climates. Aim: To describe the oral manifestations, present during dengue infection. Materials and method: A qualitative systematic review was conducted in OSF Registries. The search was conducted in PubMed, Scielo and Scopus, from June 15 to July 18, 2023, using MeSH term equations with Boolean operators. A total 299 articles were analyzed in three stages, leaving 8 studies for review. RAYYAN was used for selection and tables for study analysis. Studies were assessed under two criteria: metadata, and intraoral and extraoral manifestations of dengue. Results: The review included 8 studies, published in 2012, 2013, 2014, 2019, 2020 and 2021. The studies reported hemorrhagic dengue and type 1 dengue as diagnoses. They recorded presence of hemorrhagic and edematous gums, maculopapular lesions in the mucosa of the lower lip with pain and dysphagia, Pseudomembranous candidiasis, and edematous and erythematous taste buds. Conclusions: Reports of oral manifestations of dengue are deficient, and further research is required to enable correct diagnosis and differentiation from other pathologies.

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登革热感染期间的口腔表现:系统综述。
登革热是一个全球性的公共卫生问题,尤其是在热带和亚热带气候国家。目的:描述登革热感染时的口腔表现。材料和方法:在 OSF 登记处进行了定性系统回顾。从 2023 年 6 月 15 日至 7 月 18 日,在 PubMed、Scielo 和 Scopus 上使用 MeSH 术语方程和布尔运算符进行了搜索。共分三个阶段对 299 篇文章进行了分析,剩下 8 项研究进行了审查。使用 RAYYAN 进行筛选,并使用表格进行研究分析。研究按照两个标准进行评估:元数据以及登革热的口内和口外表现。结果:综述包括 8 项研究,分别发表于 2012 年、2013 年、2014 年、2019 年、2020 年和 2021 年。这些研究将出血性登革热和 1 型登革热作为诊断依据。他们记录了牙龈出血和水肿、下唇粘膜斑丘疹病变伴疼痛和吞咽困难、假膜性念珠菌病以及水肿和红斑味蕾。结论有关登革热口腔表现的报告尚不充分,需要进一步研究,以便正确诊断并与其他病症相鉴别。
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