Pancreatic necrosis: a scoping review.

IF 1.9 Q3 GASTROENTEROLOGY & HEPATOLOGY Minerva gastroenterology Pub Date : 2024-10-31 DOI:10.23736/S2724-5985.24.03658-1
Anthony Rainho, Mira Sridharan, Daniel S Strand
{"title":"Pancreatic necrosis: a scoping review.","authors":"Anthony Rainho, Mira Sridharan, Daniel S Strand","doi":"10.23736/S2724-5985.24.03658-1","DOIUrl":null,"url":null,"abstract":"<p><p>Acute pancreatitis (AP) is a commonly encountered GI diagnosis, accounting for 275,000 hospital admissions annually in the United States alone. Pancreatic necrosis (PN) is the most common complication of AP, and the development of PN is associated with significant morbidity and increased mortality. This expert review evaluates the evidence-based management of symptomatic PN from the era of maximal open pancreatic necrosectomy in the late 1990s though the modern paradigm of minimally invasive and endoscopic interventions. The authors present the retrospective and controlled data behind the \"step-up approach\" to PN treatment and discuss the application of current society guidance. Evidence based management of PN is characterized by early supportive care, and treatment by minimally invasive intervention when a patient is critically ill or persistently symptomatic. Appropriate choices when intervention is required include percutaneous drainage, minimally invasive surgery, and/or endoscopic treatment. The transition from open maximal necrosectomy to minimally invasive intervention has resulted in improved outcomes for patients, including gains in mortality, significant morbidity, and cost. The ideal precision management strategy for an individual patient remains an area of increasing understanding.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Minerva gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23736/S2724-5985.24.03658-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Acute pancreatitis (AP) is a commonly encountered GI diagnosis, accounting for 275,000 hospital admissions annually in the United States alone. Pancreatic necrosis (PN) is the most common complication of AP, and the development of PN is associated with significant morbidity and increased mortality. This expert review evaluates the evidence-based management of symptomatic PN from the era of maximal open pancreatic necrosectomy in the late 1990s though the modern paradigm of minimally invasive and endoscopic interventions. The authors present the retrospective and controlled data behind the "step-up approach" to PN treatment and discuss the application of current society guidance. Evidence based management of PN is characterized by early supportive care, and treatment by minimally invasive intervention when a patient is critically ill or persistently symptomatic. Appropriate choices when intervention is required include percutaneous drainage, minimally invasive surgery, and/or endoscopic treatment. The transition from open maximal necrosectomy to minimally invasive intervention has resulted in improved outcomes for patients, including gains in mortality, significant morbidity, and cost. The ideal precision management strategy for an individual patient remains an area of increasing understanding.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
胰腺坏死:范围综述。
急性胰腺炎(AP)是一种常见的消化道疾病,仅在美国,每年就有 275,000 人次入院治疗。胰腺坏死(PN)是急性胰腺炎最常见的并发症,胰腺坏死的发生与严重的发病率和死亡率增加有关。这篇专家综述评估了从上世纪 90 年代末最大限度的开放性胰腺坏死切除术时代到现代微创和内镜干预模式期间对无症状胰腺坏死的循证管理。作者介绍了 PN 治疗 "阶梯式方法 "背后的回顾性和对照数据,并讨论了当前社会指南的应用。循证治疗 PN 的特点是早期支持性护理,以及在患者病情危重或症状持续存在时进行微创介入治疗。需要干预时的适当选择包括经皮引流、微创手术和/或内窥镜治疗。从开放性最大坏死切除术到微创介入治疗的转变为患者带来了更好的治疗效果,包括降低死亡率、显著降低发病率和费用。针对个体患者的理想精准治疗策略仍是一个有待进一步了解的领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
3.10
自引率
0.00%
发文量
0
期刊最新文献
Application of artificial intelligence combined with MDT teaching model in colorectal cancer training teaching. Pancreatic necrosis: a scoping review. Evaluation of the effect of moxibustion therapy combined with press needle stimulation of bilateral Zusanli (ST36) and Neiguan (PC6) points on gastric motility recovery in patients with gastroparesis after pancreatoduodenectomy. Switching rate from intravenous to subcutaneous vedolizumab in managing inflammatory bowel diseases is lower than expected. The role and mechanisms of long non-coding RNA HOTAIR in regulating the Wnt/β-catenin signaling pathway in gastric cancer cells and its impact on tumor invasion and metastasis.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1