Blerina Resuli MD , Diego Kauffmann-Guerrero MD , Jürgen Behr MD , Amanda Tufman MD
{"title":"Simultaneous Occurrence of HER2 Mutations in EGFR Mutant NSCLC: Case Reports","authors":"Blerina Resuli MD , Diego Kauffmann-Guerrero MD , Jürgen Behr MD , Amanda Tufman MD","doi":"10.1016/j.jtocrr.2024.100719","DOIUrl":null,"url":null,"abstract":"<div><div><em>HER2</em> mutation and amplification have been identified as distinct molecular targets in lung cancer with different therapeutic and prognostic values. The coexistence of <em>HER2</em> and <em>EGFR</em> mutations is extremely rare, and therefore, no data exist on the best treatment in these cases.</div></div>","PeriodicalId":17675,"journal":{"name":"JTO Clinical and Research Reports","volume":"5 12","pages":"Article 100719"},"PeriodicalIF":3.5000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JTO Clinical and Research Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666364324000894","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/7 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
HER2 mutation and amplification have been identified as distinct molecular targets in lung cancer with different therapeutic and prognostic values. The coexistence of HER2 and EGFR mutations is extremely rare, and therefore, no data exist on the best treatment in these cases.
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