{"title":"Implementation strategy of insulin therapy under sparse state feedback","authors":"Mingzhan Huang, Shouzong Liu","doi":"10.1016/j.aml.2024.109347","DOIUrl":null,"url":null,"abstract":"<div><div>Traditional continuous glucose monitoring is often costly and inconvenient, necessitating more efficient methods. This paper proposes a novel approach to diabetes management by utilizing sparse monitoring data for insulin injection decisions. A differential equation-based model is developed to estimate plasma glucose levels and optimize insulin dosages and injection intervals using limited feedback data. This method ensures that glucose levels remain within a safe range. Numerical simulations demonstrate the effectiveness of this approach, offering a viable alternative for improving diabetes management.</div></div>","PeriodicalId":55497,"journal":{"name":"Applied Mathematics Letters","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Mathematics Letters","FirstCategoryId":"100","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0893965924003677","RegionNum":2,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Traditional continuous glucose monitoring is often costly and inconvenient, necessitating more efficient methods. This paper proposes a novel approach to diabetes management by utilizing sparse monitoring data for insulin injection decisions. A differential equation-based model is developed to estimate plasma glucose levels and optimize insulin dosages and injection intervals using limited feedback data. This method ensures that glucose levels remain within a safe range. Numerical simulations demonstrate the effectiveness of this approach, offering a viable alternative for improving diabetes management.
期刊介绍:
The purpose of Applied Mathematics Letters is to provide a means of rapid publication for important but brief applied mathematical papers. The brief descriptions of any work involving a novel application or utilization of mathematics, or a development in the methodology of applied mathematics is a potential contribution for this journal. This journal''s focus is on applied mathematics topics based on differential equations and linear algebra. Priority will be given to submissions that are likely to appeal to a wide audience.