Patient-centric decision-making in supplements intake and disclosure in clinical practice: a novel SIDP-12 tool to prevent drug-supplement interaction.

IF 3.4 3区 医学 Q2 PHARMACOLOGY & PHARMACY Therapeutic Advances in Drug Safety Pub Date : 2024-10-30 eCollection Date: 2024-01-01 DOI:10.1177/20420986241294150
Sabrina Ait Gacem, Hasniza Zaman Huri, Izyan A Wahab, Abduelmula R Abduelkarem
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Abstract

Background: Self-treatment of dietary supplements may contribute to interactions and severe side effects. Limited studies have constructed a scale that can measure the disclosure practice of supplements to healthcare providers and the influencing factors.

Objective: The study aims to investigate the supplement disclosure practice among the public in the UAE using a developed and validated supplement disclosure assessment scale tool.

Design: A cross-sectional survey study that targeted those residing in the United Arab Emirates (UAE) aged 18 years and above from both genders through an online survey.

Methods: A novel scale tool was developed and examined for its validity and reliability through three pilot studies.

Results: The study included three validity and reliability pilot studies before the main study evaluation: pilot 1 (n = 104), pilot 2 (n = 101), pilot 3 (n = 37), and study data (n = 407). A total of 407 respondents provided feedback from which 137 stated that they consumed supplements. A significant indirect effect of healthcare provider initiation of enquiry (HPE) on patient-informing practice (PI) was observed through two mediating variables, patient's beliefs (PB) and pharmacist counseling regarding supplements interactions (PC) (B = 0.106, t = 2.120, p = 0.03 and B = 0.077, t = 2.011, p = 0.04, respectively). Most respondents were not asked about their supplement consumption by the hospital and community pharmacists (52.94 and 50.74, respectively). Most respondents (54.89%) stated that pharmacists did not counsel them about any possible interaction of supplements with laboratory tests. The mean construct scores were 1.096 for PI, 2.618 for PC, 1.552 for HPE, and 1.412 for PB.

Conclusion: The instrument demonstrates desirable validity and reliability. The study results revealed a direct effect of PB and PC on the supplement disclosure practice. HPE indirectly affected PI through two mediating variables: PB and PC. The results showed a moderate HPE and PC and an excellent PB and PI construct.

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临床实践中以患者为中心的补充剂摄入和披露决策:防止药物与补充剂相互作用的新型 SIDP-12 工具。
背景:膳食补充剂的自我治疗可能会导致相互作用和严重的副作用。目前只有有限的研究构建了一个量表,用于衡量向医疗保健提供者披露补充剂的做法及其影响因素:本研究旨在使用已开发并经过验证的补充剂披露评估量表工具,调查阿联酋公众的补充剂披露情况:设计: 一项横断面调查研究,以居住在阿拉伯联合酋长国(UAE)的 18 岁及以上男女为对象,通过在线调查进行研究:方法:开发了一种新的量表工具,并通过三项试点研究对其有效性和可靠性进行了检验:在主要研究评估之前,本研究包括三项有效性和可靠性试点研究:试点 1(n = 104)、试点 2(n = 101)、试点 3(n = 37)和研究数据(n = 407)。共有 407 位受访者提供了反馈意见,其中 137 位受访者表示他们食用过保健品。通过患者的信念(PB)和药剂师关于补充剂相互作用的咨询(PC)这两个中介变量(分别为 B = 0.106,t = 2.120,p = 0.03 和 B = 0.077,t = 2.011,p = 0.04),观察到医疗服务提供者发起询问(HPE)对患者知情实践(PI)有明显的间接影响。大多数受访者没有被医院和社区药剂师询问过补充剂的服用情况(分别为 52.94 和 50.74)。大多数受访者(54.89%)表示,药剂师没有就保健品与实验室检查可能产生的相互作用向他们提供咨询。PI、PC、HPE 和 PB 的平均结构分分别为 1.096、2.618、1.552 和 1.412:结论:该工具具有理想的有效性和可靠性。研究结果表明,PB 和 PC 对补充披露实践有直接影响。HPE 通过两个中介变量间接影响 PI:PB 和 PC。研究结果表明,HPE 和 PC 的影响程度适中,PB 和 PI 的影响程度良好。
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来源期刊
Therapeutic Advances in Drug Safety
Therapeutic Advances in Drug Safety Medicine-Pharmacology (medical)
CiteScore
6.70
自引率
4.50%
发文量
31
审稿时长
9 weeks
期刊介绍: Therapeutic Advances in Drug Safety delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies pertaining to the safe use of drugs in patients. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers in drug safety, providing a forum in print and online for publishing the highest quality articles in this area. The editors welcome articles of current interest on research across all areas of drug safety, including therapeutic drug monitoring, pharmacoepidemiology, adverse drug reactions, drug interactions, pharmacokinetics, pharmacovigilance, medication/prescribing errors, risk management, ethics and regulation.
期刊最新文献
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