Diagnostic Accuracy of 4D-MRA for the Detection and Localization of Spinal Dural Arteriovenous Fistulas: A Systematic Review and Meta-Analysis

IF 2.1 4区 医学 Q3 CLINICAL NEUROLOGY World neurosurgery Pub Date : 2025-01-01 Epub Date: 2024-11-18 DOI:10.1016/j.wneu.2024.10.087
Vincent Raymaekers , Ana Rodríguez-Hernández , Sjoert A.H. Pegge , Tomas Menovsky , Frederick J.A. Meijer , Jeroen H.D. Boogaarts
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Abstract

Background

The gold standard for the diagnosis and detailed evaluation of spinal dural arteriovenous fistula (SDAVF) is a digital subtraction angiography (DSA). However, this procedure is time-consuming and effortful. A time-resolved contrast enhanced 4D magnetic resonance angiography (4D-MRA) can be used to increase the diagnostic accuracy of spinal magnetic resonance imaging for the detection and localization of a SDAVF. The goal of this study is to assess the diagnostic accuracy of 4D-MRA for the detection and localization of a SDAVF in comparison to DSA based on a systematic review of the literature.

Methods

We performed a systematic review and meta-analysis on the diagnostic accuracy of 4D-MRA compared to DSA. Literature was reviewed from the PubMed, Cochrane, and EMBASE databases.

Results

In comparison with DSA, the pooled sensitivity of MRA was 98.2% (95% confidence interval [CI] 91.5%–99.6%), with a pooled specificity of 88.2% (95% CI 57.5%–97.6%) for the diagnosis of SDAVFs. The side and level of the SDAVFs were correct in 91% (95% CI: 86%–94%) and 76% (95% CI: 71%–80%), respectively.

Conclusions

Current literature indicates that 4D-MRA has a high sensitivity and specificity for the detection and localization of a SDAVF. It can serve to guide DSA to shorten the procedural time, reduce the risk of complications, and decrease patient discomfort.
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4D-MRA 对脊髓硬脑膜动静脉瘘的检测和定位的诊断准确性:系统回顾和荟萃分析。
背景和目的:数字减影血管造影术(DSA)是诊断和详细评估脊髓硬膜动静脉瘘(SDAVF)的金标准。然而,这种方法费时费力。时间分辨对比增强磁共振血管造影序列(4D-MRA)可用于提高脊柱磁共振成像在检测和定位 SDAVF 方面的诊断准确性。本研究的目的是在对文献进行系统回顾的基础上,评估 4D-MRA 与 DSA 相比在 SDAVF 检测和定位方面的诊断准确性:我们对 4D-MRA 与 DSA 相比的诊断准确性进行了系统回顾和荟萃分析。我们从 PubMed、Cochrane 和 EMBASE 数据库中查阅了相关文献:结果:与 DSA 相比,MRA 诊断 SDAVF 的集合敏感性为 98.2%(95%CI 91.5-99.6%),集合特异性为 88.2%(95%CI 57.5-97.6%)。SDAVFs的侧面和水平的正确率分别为91%(95%CI:86-94%)和76%(95%CI:71-80%):目前的文献表明,4D-MRA 对 SDAVF 的检测和定位具有很高的灵敏度和特异性。结论:目前的文献表明,4D-MRA 对 SDAVF 的检测和定位具有较高的灵敏度和特异性,可用于指导 DSA 以缩短手术时间、降低并发症风险和减轻患者不适。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
World neurosurgery
World neurosurgery CLINICAL NEUROLOGY-SURGERY
CiteScore
3.90
自引率
15.00%
发文量
1765
审稿时长
47 days
期刊介绍: World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The journal''s mission is to: -To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care. -To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide. -To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients. Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS
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