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IF 5.5 1区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Chinese Journal of Chemistry Pub Date : 2024-11-01 DOI:10.1002/cjoc.202490235
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Abstract

Development of efficient methodologies for the synthesis of deuterium labelled compounds, especially hydrogen isotope exchange (HIE), continued to receive an impressive attention over the years. A unique heterogeneous nickel catalyst for selective deuteration of N-heterocycles has been successfully developed using D2O as the isotope source. This methodology represents a practical and scalable deuteration and the air- and water-stable nanocatalyst enables efficient labelling in a straightforward manner. More details are discussed in the article by Li et al. on pages 2993—2998.

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多年来,合成氘标记化合物的高效方法,特别是氢同位素交换(HIE)的开发一直受到广泛关注。利用 D2O 作为同位素源,成功开发出一种独特的异质镍催化剂,用于 N-杂环的选择性氘化。这种方法是一种实用的、可扩展的氘化方法,而且这种空气和水稳定的纳米催化剂能以简单的方式实现高效标记。更多详情请参见 Li 等人的文章(第 2993-2998 页)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chinese Journal of Chemistry
Chinese Journal of Chemistry 化学-化学综合
CiteScore
8.80
自引率
14.80%
发文量
422
审稿时长
1.7 months
期刊介绍: The Chinese Journal of Chemistry is an international forum for peer-reviewed original research results in all fields of chemistry. Founded in 1983 under the name Acta Chimica Sinica English Edition and renamed in 1990 as Chinese Journal of Chemistry, the journal publishes a stimulating mixture of Accounts, Full Papers, Notes and Communications in English.
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