Intrastromal Corneal Ring Segments and Keratoconus Progression: A Case Series Study.

IF 2 4区医学 Q2 OPHTHALMOLOGY Eye & Contact Lens-Science and Clinical Practice Pub Date : 2024-11-01 DOI:10.1097/ICL.0000000000001137

Blanca Benito-Pascual, Pedro Arriola-Villalobos, Olivia Rodríguez-Quet, Vittoria Termine, Ricardo Cuiña-Sardiña, David Díaz-Valle

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Abstract

Objective: To assess keratoconus (KC) progression following the implant of intrastromal corneal ring segments (ICRSs) in young patients.

Materials and methods: Retrospective, longitudinal, observational, controlled nonrandomized case series study. Keratoconus patients aged 25 years or younger who underwent uneventful ICRS surgery and completed at least 3 years of follow-up were enrolled. Controls were of similar age and treatment-naive patients with KC. The following Pentacam imaging (Oculus, Wetzlar, Germany) data were analyzed: keratometric (maximum, in-flattest meridian, in-steepest meridian, and mean), aberrometric (higher-order aberrations and coma), pachymetric (thinnest corneal thickness), and elevation (maximum posterior elevation). The main outcome measure was KC progression.

Results: The study sample comprised 20 eyes of 18 cases (age 20.20 ± 3.70 years, nine right eyes, 14 male patients) and 30 eyes of 24 controls (age 20.80 ± 3.20 years, 15 right eyes, 21 male patients). The mean follow-up duration was 4.90 ± 1.70 years (range 3-8 years) for cases and 4.50 ± 1.40 years (range 3-8 years) for controls. Four cases and two controls met criteria for KC progression.

Conclusions: Intrastromal corneal ring segments did not have significant impact on KC progression in the cohort.

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角膜环内节段与角膜炎进展：病例系列研究。

摘要评估年轻患者植入基质内角膜环（ICRS）后角膜炎（KC）的进展情况：回顾性、纵向、观察性、对照性非随机病例系列研究。研究对象为年龄在 25 岁或以下、接受了顺利的 ICRS 手术并完成了至少 3 年随访的角膜塑形镜患者。对照组为年龄相仿、未接受过治疗的 KC 患者。对以下 Pentacam 成像（Oculus，德国韦茨拉尔）数据进行了分析：角膜度数（最大值、最平子午线、最陡子午线和平均值）、像差（高阶像差和昏迷）、角膜厚度（最薄角膜厚度）和角膜抬高（最大后方抬高）。主要结果指标为 KC 进展：研究样本包括 18 名病例的 20 只眼睛（年龄为 20.20 ± 3.70 岁，9 名右眼患者，14 名男性患者）和 24 名对照组的 30 只眼睛（年龄为 20.80 ± 3.20 岁，15 名右眼患者，21 名男性患者）。病例的平均随访时间为 4.90 ± 1.70 年（3-8 年不等），对照组为 4.50 ± 1.40 年（3-8 年不等）。4例病例和2例对照组符合KC进展标准：结论：基质内角膜环段对队列中的 KC 进展没有显著影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Eye & Contact Lens-Science and Clinical Practice OPHTHALMOLOGY-

CiteScore

4.50

自引率

4.30%

发文量

150

审稿时长

6-12 weeks

期刊介绍： Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.